SCHEMBL3373753

SCHEMBL3373753

Cc1ccc(-c2nc(CI)c(-c3ccccc3)o2)cc1.Cc1ccc(-c2nc(COCCCOCc3cccc(C)c3C(=O)O)c(-c3ccccc3)o2)cc1

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPARG P37231 10/20 0.38
PPARA Q07869 8/20 0.38
TP53 P04637 1/20 0.36
ANO1 Q5XXA6 2/20 0.36
KDM4E B2RXH2 1/20 0.36
PPARD Q03181 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
DPP4 P27487 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3292431 0.95 PPARG (0.41) PPARGPPARATP53ANO1KDM4E
SCHEMBL3371224 0.89 PPARG (0.43) PPARGPPARATP53KDM4EPPARD
SCHEMBL3370847 0.87 PPARG (0.45) PPARGPPARATP53KDM4EPPARD
SCHEMBL3368702 0.87 PPARA (0.41) PPARGPPARATP53PPARD
SCHEMBL3298881 0.86 PPARG (0.46) PPARGPPARATP53KDM4EPPARD
SCHEMBL3317048 0.84 PPARG (0.48) PPARGPPARATP53KDM4EPPARD
SCHEMBL13114657 0.84 KDM4E (0.48) PPARGPPARATP53KDM4EPPARD
SCHEMBL3314538 0.83 PPARA (0.44) PPARGPPARATP53PPARD
SCHEMBL3370914 0.83 MEN1 (0.35) PPARGPPARATP53KDM4E
SCHEMBL3369918 0.82 PPARG (0.43) PPARGPPARATP53PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1902039-B1 6-OXAZOL-4-YLMETHOXY-ALKOXYMETHYL SUBSTITUTED BENZOIC ACID DERIVATIVES FORMING PPAR LIGANDS, METHODS FOR PRODUCTION AND THE USE THEREOF IN THE FORM OF DRUGS SANOFI AVENTIS (FR) 2010-10-13 EP disclosed
EP-1902039-A1 6-OXAZOL-4-YLMETHOXY-ALKOXYMETHYL SUBSTITUTED BENZOIC ACID DERIVATIVES FORMING PPAR LIGANDS, METHODS FOR PRODUCTION AND THE USE THEREOF IN THE FORM OF DRUGS Sanofi-Aventis (FR) 2008-03-26 EP disclosed
WO-2007000235-A1 6-OXAZOL-4-YLMETHOXY-ALKOXYMETHYL SUBSTITUTED BENZOIC ACID DERIVATIVES FORMING PPAR LIGANDS, METHODS FOR PRODUCTION AND THE USE THEREOF IN THE FORM OF DRUGS SANOFI-AVENTIS (DE) 2007-01-04 WO disclosed