Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31255814 | 1.00 | LCK (0.43) | LCKAPPBACE1TRPM4KDM4E | |
| SCHEMBL31255815 | 0.95 | LCK (0.42) | LCKAPPBACE1TRPM4KDM4E | |
| SCHEMBL5358508 | 0.95 | LCK (0.42) | LCKAPPBACE1TRPM4KDM4E | |
| SCHEMBL22863439 | 0.82 | LCK (0.36) | LCKAPPBACE1TRPM4KDM4E | |
| SCHEMBL30311029 | 0.82 | ALOX15 (0.39) | LCKAPPLMNACYP3A4HPGD | |
| SCHEMBL6357305 | 0.82 | ALOX15 (0.39) | LCKAPPLMNACYP3A4HPGD | |
| SCHEMBL6346339 | 0.82 | KDM4E (0.48) | LCKKDM4EALDH1A1CYP3A4MAPT | |
| SCHEMBL5011026 | 0.79 | TRPM4 (0.52) | LCKTRPM4KDM4ECA12ALDH1A1 | |
| SCHEMBL9430387 | 0.79 | TRPM4 (0.52) | LCKTRPM4KDM4ECA12ALDH1A1 | |
| SCHEMBL633810 | 0.79 | TRPM4 (0.52) | LCKTRPM4KDM4ECA12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651596-B | Epoxy resin containing naphthalene ring structure and preparation method thereof | 上海华谊树脂有限公司 | 2021-11-09 | — | — | CN | claimed |
| US-11858814-B2 | Reticulation of macromolecules into crystalline networks | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-01-02 | — | — | US | disclosed |
| CN-109651596-B | Epoxy resin containing naphthalene ring structure and preparation method thereof | 上海华谊树脂有限公司 | 2021-11-09 | — | — | CN | disclosed |
| US-20210087064-A1 | RETICULATION OF MACROMOLECULES INTO CRYSTALLINE NETWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-03-25 | — | — | US | disclosed |
| CN-109651596-A | A kind of epoxy resin and preparation method thereof containing naphthalene ring | 上海华谊树脂有限公司 | 2019-04-19 | — | — | CN | disclosed |
| EP-2738222-B1 | THERMOPLASTIC RESIN COMPOSITION FOR IMPACT ABSORBING MEMBER AND METHOD FOR PRODUCING SAME | TORAY INDUSTRIES (JP) | 2018-09-26 | — | — | EP | disclosed |
| EP-2003158-B1 | DENDRITIC POLYESTER, METHOD FOR PRODUCING THE SAME, AND THERMOPLASTIC RESIN COMPOSITION | TORAY INDUSTRIES (JP) | 2017-07-05 | — | — | EP | disclosed |
| US-9394482-B2 | Polymerizable compound, polymerizable composition and liquid crystal display device | JNC CORPORATION (JP) | 2016-07-19 | — | — | US | disclosed |
| US-9394482-B2 | Polymerizable compound, polymerizable composition and liquid crystal display device | JNC CORPORATION (JP) | 2016-07-19 | — | — | US | disclosed |
| US-9334482-B2 | Thermoplastic resin composition for impact absorbing member and method for producing same | TORAY INDUSTRIES, INC. (JP) | 2016-05-10 | — | — | US | disclosed |
| US-8258197-B2 | Synthesis of a highly crystalline, covalently linked porous network | UNIVERSITY OF SOUTH CAROLINA (US) | 2012-09-04 | — | — | US | disclosed |
| US-8258197-B2 | Synthesis of a highly crystalline, covalently linked porous network | UNIVERSITY OF SOUTH CAROLINA (US) | 2012-09-04 | — | — | US | disclosed |
| US-20120215015-A1 | PREPARATION OF METAL-CATECHOLATE FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-08-23 | — | — | US | disclosed |
| US-20120215015-A1 | PREPARATION OF METAL-CATECHOLATE FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-08-23 | — | — | US | disclosed |
| US-8097685-B2 | Dendritic polymer, method for producing the same, and thermoplastic resin composition | TORAY INDUSTRIES, INC. (JP) | 2012-01-17 | — | — | US | disclosed |
| US-20090227697-A1 | SYNTHESIS OF A HIGHLY CRYSTALLINE, COVALENTLY LINKED POROUS NETWORK | NATIONAL SCIENCE FOUNDATION | 2009-09-10 | — | — | US | disclosed |
| US-20090118417-A1 | Dendritic Polymer, Method for Producing the Same, and Thermoplastic Resin Composition | TORAY INDUSTRIES, INC. (JP) | 2009-05-07 | — | — | US | disclosed |
| EP-2003158-A9 | DENDRITIC POLYESTER, METHOD FOR PRODUCING THE SAME, AND THERMOPLASTIC RESIN COMPOSITION | TORAY INDUSTRIES, INC. (JP) | 2009-05-06 | — | — | EP | disclosed |
| EP-2003158-A2 | DENDRITIC POLYESTER, METHOD FOR PRODUCING THE SAME, AND THERMOPLASTIC RESIN COMPOSITION | TORAY INDUSTRIES, INC. (JP) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007098263-A2 | SYNTHESIS OF A HIGHLY CRYSTALLINE, COVALENTLY LINKED POROUS NETWORK | UNIVERSITY OF SOUTH CAROLINA (US) | 2007-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120215015-A1 | PREPARATION OF METAL-CATECHOLATE FRAMEWORKS | COMT, MCU, CTCF | LCK 1441/4885APP 4588/4885BACE1 4307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.