Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 4/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ALPG | P10696 | 1/20 | 0.30 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3372729 | 0.85 | PPARD (0.34) | PPARDESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL3032424 | 0.84 | PPARD (0.55) | PPARDPPARA | |
| SCHEMBL3032421 | 0.84 | PPARD (0.55) | PPARDPPARA | |
| SCHEMBL3032217 | 0.81 | PPARA (0.43) | PPARDPPARA | |
| SCHEMBL3034484 | 0.81 | PPARA (0.43) | PPARDPPARA | |
| SCHEMBL3373878 | 0.79 | PPARD (0.48) | PPARDPPARACYP3A4ALPG | |
| SCHEMBL3375669 | 0.76 | PPARD (0.44) | PPARDPPARACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL3372723 | 0.74 | PPARD (0.36) | PPARDPPARAGAA | |
| SCHEMBL3372726 | 0.74 | PPARD (0.36) | PPARDPPARAGAA | |
| SCHEMBL3375341 | 0.72 | PPARD (0.44) | PPARDCYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745002-B1 | NOVEL COMPOUNDS, THEIR PREPARATION AND USE | HIGH POINT PHARMACEUTICALS LLC (US) | 2010-11-03 | — | — | EP | claimed |