Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14565942 | 0.89 | TSHR (0.51) | POLBLMNAMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL721026 | 0.87 | MAPT (0.51) | POLBLMNAMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL3194809 | 0.85 | POLB (0.53) | POLBLMNAMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL13144353 | 0.85 | POLB (0.53) | POLBLMNAMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL819038 | 0.85 | POLB (0.53) | POLBLMNAMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL28725873 | 0.83 | POLB (0.50) | POLBLMNAMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL31040362 | 0.83 | TDP1 (0.51) | POLBLMNATSHRESR1ESR2 | |
| SCHEMBL10901654 | 0.83 | POLB (0.50) | POLBLMNAMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL15713256 | 0.83 | POLB (0.55) | POLBLMNAMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL14173333 | 0.83 | POLB (0.55) | POLBLMNAMAPTNPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2236122-B1 | Polymer-modified glass ionomer cement | VOCO GMBH (DE) | 2017-08-30 | — | — | EP | disclosed |
| EP-1839640-B1 | Curable dental materials | VOCO GMBH (DE) | 2010-11-03 | — | — | EP | disclosed |
| EP-2236122-A2 | Polymer-modified glass ionomer cement | VOCO GmbH (DE) | 2010-10-06 | — | — | EP | disclosed |
| EP-1839640-A2 | Curable dental materials | VOCO GmbH (DE) | 2007-10-03 | — | — | EP | disclosed |