⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL942172 | 0.85 | — | — | |
| SCHEMBL7110611 | 0.81 | — | — | |
| SCHEMBL10264199 | 0.81 | — | — | |
| SCHEMBL13827864 | 0.77 | NOS2 (0.57) | — | |
| SCHEMBL12432408 | 0.77 | ALDH1A1 (0.41) | — | |
| SCHEMBL18701490 | 0.77 | ALDH1A1 (0.43) | — | |
| SCHEMBL9228677 | 0.77 | NOS2 (0.57) | — | |
| SCHEMBL10367813 | 0.77 | S1PR2 (0.38) | — | |
| Morpholine SCHEMBL11199826 | 0.76 | MEN1 (0.41) | — | |
| SCHEMBL10367812 | 0.75 | NPC1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4526 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4608363-A1 | A COMPOSITION FOR IMPROVING EFFECTIVENESS OF DYE PRECURSORS FOR CHANGE OF COLOUR OF HAIR | Cavinkare Pvt. Ltd (IN) | 2025-09-03 | — | — | EP | claimed |
| WO-2024089704-A1 | A COMPOSITION FOR IMPROVING EFFECTIVENESS OF DYE PRECURSORS FOR CHANGE OF COLOUR OF HAIR | CAVINKARE PVT.LTD. (IN) | 2024-05-02 | — | — | WO | claimed |
| CN-114591225-B | Method for large-scale production of 2, 6-dibromo-4-methylpyridine | 河南阿尔法医药科技有限公司 | 2024-02-06 | — | — | CN | claimed |
| US-11555017-B2 | Oxidation base derived from 1-hexyl-4,5-diaminopyrazole, composition containing same and use thereof in oxidation dyeing of keratin fibres | L'OREAL (FR) | 2023-01-17 | — | — | US | claimed |
| US-20220183940-A1 | DYEING PROCESS USING PEROXYGENATED SALTS AND A SUBSTRATE COMPRISING OXIDATION DYES | L'OREAL (FR) | 2022-06-16 | — | — | US | claimed |
| CN-114591225-A | Method for large-scale production of 2, 6-dibromo-4-methylpyridine | 河南阿尔法医药科技有限公司 | 2022-06-07 | — | — | CN | claimed |
| CN-112834643-B | Method for measuring 2, 6-dihydroxy-4-methylpyridine and 2, 6-dihydroxy-3-cyano-4-methylpyridine | 郑州原理生物科技有限公司 | 2022-03-18 | — | — | CN | claimed |
| EP-3946217-A1 | DYEING PROCESS USING PEROXYGENATED SALTS AND A SUBSTRATE COMPRISING OXIDATION DYES | L'OREAL (FR) | 2022-02-09 | — | — | EP | claimed |
| CN-112834643-A | Method for measuring 2, 6-dihydroxy-4-methylpyridine and 2, 6-dihydroxy-3-cyano-4-methylpyridine | 郑州原理生物科技有限公司 | 2021-05-25 | — | — | CN | claimed |
| CN-112089633-A | Oxidation dyeing method | 莱雅公司 | 2020-12-18 | — | — | CN | claimed |
| EP-0926149-A1 | Keratin fibre dye composition containing 3-aminopyrazolo-(1,5-a)-pyrimidines, dyeing method , 3-aminopyrazolo-(1,5-a)-pyrimidines and their preparation | L'OREAL (FR) | 1999-06-30 | — | — | EP | claimed |
| EP-0923929-A1 | KERATIN FIBRE DYE COMPOSITION CONTAINING PYRAZOLO-AZOLE COMPOUNDS, USE THEREOF AS OXIDATION AGENTS, AND DYEING METHOD; PYRAZOLOAZOLES | L'OREAL (FR) | 1999-06-23 | — | — | EP | claimed |
| WO-1999017728-A1 | OXIDATION DYEING COMPOSITION FOR KERATIN FIBRES | L'OREAL (FR) | 1999-04-15 | — | — | WO | claimed |
| US-5785717-A | Composition for the oxidation dyeing of keratin fibers, comprising a diaminopyrazole derivative and a heterocyclic coupler, and dyeing process | L'OREAL (FR) | 1998-07-28 | — | — | US | claimed |
| US-5769903-A | Composition for the oxidation dyeing of keratin fibers, comprising an oxidation base, an indole coupler and an additional heterocyclic coupler, and dyeing process | L'OREAL (FR) | 1998-06-23 | — | — | US | claimed |
| EP-0728464-B1 | Composition for dyeing keratinous fibers comprising a diaminopyrazole derivative and a heterocyclic coupleur and dyeing process | OREAL (FR) | 1997-07-30 | — | — | EP | claimed |
| EP-0728466-A1 | Keratinous fibers oxidation dyeing composition comprising an oxidation base, an indolic coupler and an additional heterocyclic coupler and dyeing process | L'OREAL (FR) | 1996-08-28 | — | — | EP | claimed |
| EP-0728464-A1 | Composition for dyeing keratinous fibers comprising a diaminopyrazole derivative and a heterocyclic coupleur and dyeing process | L'OREAL (FR) | 1996-08-28 | — | — | EP | claimed |
| US-4904275-A | OXIDIZER | L'OREAL (FR) | 1990-02-27 | — | — | US | claimed |
| US-4157446-A | REACTION OF 4-METHYL-2,6-DIHYDROXYPYRIDINE WITH TRIHALOACETALDEHYDE | CASSELLA AKTIENGESELLSCHAFT (DE) | 1979-06-05 | — | — | US | claimed |