Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 18/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 15/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 15/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 15/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3374398 | 0.84 | PDE4B (0.57) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3375212 | 0.83 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5823060 | 0.79 | PDE4A (0.77) | PDE4APDE4BPDE4CPDE4DS1PR1 | |
| SCHEMBL7359419 | 0.76 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4DS1PR1 | |
| SCHEMBL3375194 | 0.76 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4DS1PR1 | |
| SCHEMBL5818764 | 0.73 | PDE4A (0.76) | PDE4APDE4BPDE4CPDE4DS1PR1 | |
| SCHEMBL6919617 | 0.73 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7364691 | 0.73 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7696540 | 0.73 | PDE4A (0.72) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28187722 | 0.72 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4DS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2172458-A1 | PYRAZOLONE DERIVATIVE | Kowa Company, Ltd. (JP) | 2010-04-07 | — | — | EP | disclosed |