Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 10/20 | 0.57 |
| ▸ | PDE4A | P27815 | 8/20 | 0.57 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3375187 | 0.86 | PDE4B (0.57) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3373322 | 0.84 | PDE4A (0.55) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3374189 | 0.78 | PDE4B (0.58) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3374185 | 0.74 | KDM4E (0.64) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3375212 | 0.74 | PDE4A (0.56) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3371490 | 0.74 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7361110 | 0.74 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL7355624 | 0.73 | PDE4B (0.57) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL497890 | 0.73 | PDE4B (0.57) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL498539 | 0.71 | ALDH1A1 (0.60) | PDE4BPDE4APDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2172458-A1 | PYRAZOLONE DERIVATIVE | Kowa Company, Ltd. (JP) | 2010-04-07 | — | — | EP | disclosed |