Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 3/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3370494 | 0.87 | ANPEP (0.31) | MMP2MMP1ANPEP | |
| SCHEMBL3372484 | 0.79 | TSHR (0.31) | CA1CA2TSHRGRIN2DGRIN3B | |
| SCHEMBL28500663 | 0.75 | MMP2 (0.41) | MMP2CA1CA2ALOX15FDPS | |
| SCHEMBL2589834 | 0.75 | — | — | |
| SCHEMBL6832394 | 0.73 | MMP2 (0.40) | MMP2CA1CA2ALOX15FDPS | |
| SCHEMBL5702606 | 0.71 | — | — | |
| SCHEMBL10795682 | 0.69 | MMP2 (0.44) | MMP2CA1CA2ALOX15MMP1 | |
| SCHEMBL4797826 | 0.69 | ALDH1A1 (0.43) | ADH1BADH1CADH1AADH7TSHR | |
| SCHEMBL10873346 | 0.67 | S1PR2 (0.45) | ADH1BADH1CADH1AADH7TSHR | |
| SCHEMBL10877503 | 0.67 | S1PR2 (0.45) | ADH1BADH1CADH1AADH7TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756125-B1 | 1,1,3,3,3-PENTAAMINO-1-OXO/THIO-1LAMBDA5,3LAMBDA5-DIPHOSPHAZ-2-ENES, METHOD FOR PRODUCING THEM AND THEIR USE AS AGENTS FOR REGULATING OR INHIBITING ENZYMATIC HYDROLYSIS OF UREA | PIESTERITZ STICKSTOFF (DE) | 2010-11-10 | — | — | EP | disclosed |
| EP-1756125-A1 | 1,1,3,3,3-PENTAAMINO-1LAMBDA5,3LAMBDA5-DIPHOSPHAZ-2-ENES, METHOD FOR PRODUCING THEM AND THEIR USE AS AGENTS FOR REGULATING OR INHIBITING ENZYMATIC HYDROLYSIS OF UREA | SKW STICKSTOFFWERKE PIESTERITZ GmbH (DE) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005118602-A1 | 1,1,3,3,3-PENTAAMINO-1λ5,3λ5-DIPHOSPHAZ-2-ENES, METHOD FOR PRODUCING THEM AND THEIR USE AS AGENTS FOR REGULATING OR INHIBITING ENZYMATIC HYDROLYSIS OF UREA | SKW STICKSTOFFWERKE PIESTERITZ GMBH (DE) | 2005-12-15 | — | — | WO | disclosed |