Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3373703 | 0.93 | KMT2A (0.67) | KMT2AMEN1RAB9ASLC6A2SLC6A4 | |
| SCHEMBL3373916 | 0.89 | KMT2A (0.60) | KMT2AMEN1RAB9ASLC6A2SLC6A4 | |
| SCHEMBL11794019 | 0.87 | KMT2A (0.56) | KMT2AMEN1RAB9ASLC6A2SLC6A4 | |
| SCHEMBL4489240 | 0.84 | SLC6A2 (0.73) | KMT2AMEN1RAB9ASLC6A2SLC6A4 | |
| SCHEMBL31687534 | 0.83 | KMT2A (0.51) | KMT2AMEN1RAB9ASLC6A2SLC6A4 | |
| SCHEMBL17984967 | 0.83 | KMT2A (0.51) | KMT2AMEN1RAB9ASLC6A2SLC6A4 | |
| SCHEMBL3376642 | 0.83 | KMT2A (0.57) | KMT2AMEN1RAB9ASLC6A2SLC6A4 | |
| SCHEMBL3371525 | 0.82 | GRIN2B (0.63) | KMT2AMEN1RAB9ASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL31687542 | 0.81 | KMT2A (0.50) | KMT2AMEN1RAB9ASLC6A2SLC6A4 | |
| SCHEMBL3376962 | 0.81 | YTHDC1 (0.58) | KMT2AMEN1RAB9ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324091-A1 | Pyrazolone Derivative | KOWA COMPANY, LTD. (JP) | 2010-12-23 | — | — | US | disclosed |
| EP-2172458-A1 | PYRAZOLONE DERIVATIVE | Kowa Company, Ltd. (JP) | 2010-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324091-A1 | Pyrazolone Derivative | SERPINE1, SERPINC1, TFPI | KMT2A 4670/4885MEN1 2985/4885RAB9A 3319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.