Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8853723 | 1.00 | SMN1; SMN2 (0.33) | SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL3369038 | 1.00 | SMN1; SMN2 (0.33) | SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL19601183 | 0.80 | ALDH1A1 (0.33) | SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL19356247 | 0.79 | ALDH1A1 (0.35) | ALDH1A1TSHR | |
| SCHEMBL15631557 | 0.79 | — | — | |
| SCHEMBL14882817 | 0.79 | ALDH1A1 (0.32) | ALDH1A1TSHR | |
| SCHEMBL11753823 | 0.77 | SMN1; SMN2 (0.31) | SMN1; SMN2 | |
| SCHEMBL18193404 | 0.77 | CA1 (0.37) | TSHR | |
| SCHEMBL10358513 | 0.77 | — | — | |
| SCHEMBL14883033 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771454-B1 | HEPATITIS C INHIBITOR PEPTIDE ANALOGS | BOEHRINGER INGELHEIM INT (DE) | 2011-06-15 | — | — | EP | disclosed |
| EP-1599496-B1 | HEPATITIS C INHIBITOR PEPTIDE ANALOGS | BOEHRINGER INGELHEIM INT (DE) | 2010-11-03 | — | — | EP | disclosed |
| EP-1599496-B1 | HEPATITIS C INHIBITOR PEPTIDE ANALOGS | BOEHRINGER INGELHEIM INT (DE) | 2010-11-03 | — | — | EP | disclosed |
| US-7696242-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-13 | — | — | US | disclosed |
| US-7696242-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-13 | — | — | US | disclosed |
| WO-2006007708-A1 | HEPATITIS C INHIBITOR PEPTIDE ANALOGS | BOEHRINGER ENGELHEIM INTERNATIONAL GMBH (DE) | 2006-01-26 | — | — | WO | disclosed |
| EP-1599496-A2 | HEPATITIS C INHIBITOR PEPTIDE ANALOGS | Boehringer Ingelheim International GmbH (DE) | 2005-11-30 | — | — | EP | disclosed |
| US-6908901-B2 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL, GMBH (DE) | 2005-06-21 | — | — | US | disclosed |
| WO-2004101602-A2 | HEPATITIS C INHIBITOR PEPTIDE ANALOGS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-11-25 | — | — | WO | disclosed |
| US-20040224900-A1 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-11-11 | — | — | US | disclosed |
| US-20040224900-A1 | Hepatitis C inhibitor peptide analogs | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040224900-A1 | Hepatitis C inhibitor peptide analogs | RNASE1, HAVCR2, CTRL | SMN1; SMN2 4347/4885ALDH1A1 2344/4885TSHR 2135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.