Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.72 |
| ▸ | HTR1A | P08908 | 1/20 | 0.72 |
| ▸ | DRD4 | P21917 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Zalospirone SCHEMBL247562 | 1.00 | DRD2 (0.72) | DRD2HTR1ADRD4 | |
| Zalospirone SCHEMBL17256233 | 1.00 | DRD2 (0.72) | DRD2HTR1ADRD4 | |
| Zalospirone SCHEMBL9526873 | 1.00 | DRD2 (0.72) | DRD2HTR1ADRD4 | |
| Zalospirone SCHEMBL13532604 | 1.00 | DRD2 (0.72) | DRD2HTR1ADRD4 | |
| Zalospirone SCHEMBL247563 | 1.00 | DRD2 (0.72) | DRD2HTR1ADRD4 | |
| Zalospirone SCHEMBL123826 | 0.99 | DRD2 (0.72) | DRD2HTR1ADRD4 | |
| SCHEMBL9527393 | 0.91 | DRD2 (0.71) | DRD2HTR1ADRD4 | |
| SCHEMBL9528185 | 0.91 | DRD2 (0.71) | DRD2HTR1ADRD4 | |
| SCHEMBL17264052 | 0.91 | DRD2 (0.71) | DRD2HTR1ADRD4 | |
| SCHEMBL13534443 | 0.91 | DRD2 (0.71) | DRD2HTR1ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012002583-A1 | METHOD FOR TREATING SCHIZOPHRENIA AND RELATED DISEASES WITH A COMBINATION THERAPY | VANDERBILT UNIVERSITY (US) | 2012-01-05 | — | — | WO | disclosed |