⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL337442 | 1.00 | — | — | |
| SCHEMBL2009746 | 0.79 | — | — | |
| SCHEMBL13417414 | 0.77 | TSHR (0.35) | — | |
| Ethane SCHEMBL10659912 | 0.77 | TDP1 (0.40) | — | |
| SCHEMBL3583584 | 0.77 | SPHK2 (0.37) | — | |
| SCHEMBL24111165 | 0.77 | TSHR (0.35) | — | |
| SCHEMBL3583586 | 0.77 | SPHK2 (0.37) | — | |
| SCHEMBL13417353 | 0.77 | TSHR (0.35) | — | |
| SCHEMBL13417354 | 0.75 | TSHR (0.33) | — | |
| SCHEMBL15750870 | 0.73 | LMNA (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3124490-A1 | HIGH STABILITY POLYIONIC LIQUID SALTS | Sigma-Aldrich Co. LLC (US) | 2017-02-01 | — | — | EP | disclosed |
| EP-2114969-B1 | HIGH STABILITY POLYIONIC LIQUID SALTS | SIGMA ALDRICH CO LLC (US) | 2016-06-29 | — | — | EP | disclosed |
| US-8481722-B2 | High stability polyionic liquid salts | SIGMA-ALDRICH CO. LLC (US) | 2013-07-09 | — | — | US | disclosed |
| US-20120083603-A1 | HIGH STABILITY POLYIONIC LIQUID SALTS | SIGMA-ALDRICH CO. LLC (US) | 2012-04-05 | — | — | US | disclosed |
| US-8097721-B2 | polycationic or polyanionic molecules; use as stationary phases in gas chromatography, and as a reagent in electrospray ionization-mass spectrometry (ESI-MS); thermal stability; tris(anion) such as tris(sulfonate) or tris(cation) groups such as imidazolium, pyrrolidinium, ammonium | SIGMA-ALDRICH CO. LLC (US) | 2012-01-17 | — | — | US | disclosed |
| US-20080210858-A1 | High Stability Polyionic Liquid Salts | SIGMA-ALDRICH CO. NEWCO INC. | 2008-09-04 | — | — | US | disclosed |
| US-20050130941-A1 | Methods of treating alzheimer's disease | PHARMACIA & UPJOHN COMPANY LLC | 2005-06-16 | — | — | US | disclosed |
| US-6900313-B2 | Chiral ionic liquids | MERCK PATENT GMBH (DE) | 2005-05-31 | — | — | US | disclosed |
| EP-1250299-B1 | CHIRAL IONIC LIQUIDS | SOLVENT INNOVATION GMBH (DE) | 2005-04-06 | — | — | EP | disclosed |
| EP-1392315-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2004-03-03 | — | — | EP | disclosed |
| US-20030149264-A1 | Chiral ionic liquids | SOLVENT INNOVATION GMBH (DE) | 2003-08-07 | — | — | US | disclosed |
| WO-2002100410-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | disclosed |
| EP-1250299-A2 | CHIRAL IONIC LIQUIDS | Solvent Innovation GmbH (DE) | 2002-10-23 | — | — | EP | disclosed |
| WO-2001055060-A2 | CHIRAL IONIC LIQUIDS | SOLVENT INNOVATION GMBH (DE) | 2001-08-02 | — | — | WO | disclosed |
| US-5753652-A | Antiretroviral hydrazine derivatives | NOVARTIS CORPORATION (US) | 1998-05-19 | — | — | US | disclosed |
| EP-0521827-B1 | Pharmacological active hydrazin derivatives and process for their preparation | CIBA GEIGY AG (CH) | 1996-09-25 | — | — | EP | disclosed |
| EP-0521827-A1 | Pharmacological active hydrazin derivatives and process for their preparation | CIBA-GEIGY AG (CH) | 1993-01-07 | — | — | EP | disclosed |