Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.37 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3583584 | 1.00 | SPHK2 (0.37) | SPHK2SPHK1CETPTSHRTDP1 | |
| SCHEMBL13452816 | 0.79 | TSHR (0.32) | TSHR | |
| SCHEMBL10941781 | 0.79 | TSHR (0.32) | SPHK2SPHK1CETPTSHRTDP1 | |
| SCHEMBL337442 | 0.77 | — | — | |
| SCHEMBL337443 | 0.77 | — | — | |
| SCHEMBL25058928 | 0.76 | SPHK2 (0.40) | SPHK2SPHK1CETPTSHRTDP1 | |
| SCHEMBL3580467 | 0.76 | PGR (0.36) | TSHRTDP1 | |
| SCHEMBL3580466 | 0.76 | PGR (0.36) | TSHRTDP1 | |
| SCHEMBL21428147 | 0.75 | SPHK1 (0.49) | SPHK2SPHK1CETP | |
| SCHEMBL2009746 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056575-A1 | Anesthetic Compounds | SIGNATURE THERAPEUTICS, INC. | 2010-03-04 | — | — | US | disclosed |
| EP-2069299-A2 | ANESTHETIC COMPOUNDS | Pharmacofore, Inc. (US) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008011539-A2 | ANESTHETIC COMPOUNDS | PHARMACOFORE, INC. (US) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056575-A1 | Anesthetic Compounds | OPRL1, OPRM1, CYP3A5 | SPHK2 3042/4885SPHK1 2705/4885CETP 3307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.