Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | HPRT1 | P00492 | 9/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | TYMP | P19971 | 3/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14645672 | 0.80 | FGFR1 (0.54) | CYP3A4FGFR1HPRT1SLC22A6TYMP | |
| SCHEMBL5065338 | 0.80 | FGFR1 (0.54) | CYP3A4FGFR1HPRT1SLC22A6TYMP | |
| SCHEMBL5030842 | 0.75 | CYP3A4 (0.64) | CYP3A4FGFR1SLC22A6ALDH1A1LMNA | |
| SCHEMBL18934361 | 0.73 | DNMT1 (0.36) | GMNNALDH1A1LMNATP53NFKB1 | |
| SCHEMBL19923817 | 0.71 | DNMT1 (0.35) | GMNNALDH1A1LMNATP53NFKB1 | |
| SCHEMBL1095404 | 0.70 | FGFR1 (0.67) | CYP3A4FGFR1HPRT1SLC22A6TYMP | |
| SCHEMBL1095071 | 0.70 | FGFR1 (0.67) | CYP3A4FGFR1HPRT1SLC22A6TYMP | |
| SCHEMBL28677450 | 0.70 | FGFR1 (0.54) | CYP3A4FGFR1HPRT1SLC22A6TYMP | |
| SCHEMBL12451367 | 0.70 | CDK1 (0.47) | GMNNALDH1A1LMNATP53NFKB1 | |
| SCHEMBL5280050 | 0.68 | FGFR1 (0.57) | CYP3A4FGFR1HPRT1SLC22A6TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966226-B1 | AZACYTOSINE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | LEUVEN K U RES & DEV (BE) | 2010-11-10 | — | — | EP | disclosed |