Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525515 | 1.00 | HTR1A (1.00) | HTR1A | |
| SCHEMBL8812229 | 0.86 | HTR1A (0.76) | HTR1A | |
| SCHEMBL8812236 | 0.86 | HTR1A (0.76) | HTR1A | |
| SCHEMBL8814466 | 0.86 | HTR1A (0.76) | HTR1A | |
| SCHEMBL9080563 | 0.82 | HTR1A (1.00) | HTR1A | |
| SCHEMBL9080567 | 0.82 | HTR1A (1.00) | HTR1A | |
| SCHEMBL8816430 | 0.81 | HTR1A (0.68) | HTR1A | |
| Hydrochloric Acid SCHEMBL8900402 | 0.81 | HTR1A (0.97) | HTR1A | |
| Hydrochloric Acid SCHEMBL8900399 | 0.81 | HTR1A (0.97) | HTR1A | |
| SCHEMBL8808085 | 0.79 | HTR1A (0.73) | HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012002583-A1 | METHOD FOR TREATING SCHIZOPHRENIA AND RELATED DISEASES WITH A COMBINATION THERAPY | VANDERBILT UNIVERSITY (US) | 2012-01-05 | — | — | WO | disclosed |
| EP-0892963-A1 | METHOD OF CREATING AND SEARCHING A MOLECULAR VIRTUAL LIBRARY USING VALIDATED MOLECULAR STRUCTURE DESCRIPTORS | Patterson, David E. (US) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997027559-A1 | METHOD OF CREATING AND SEARCHING A MOLECULAR VIRTUAL LIBRARY USING VALIDATED MOLECULAR STRUCTURE DESCRIPTORS | PATTERSON DAVID E (US) | 1997-07-31 | — | — | WO | disclosed |