Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.68 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8814466 | 0.94 | HTR1A (0.76) | HTR1AHTR2AHTR2CHTR2B | |
| SCHEMBL8812229 | 0.81 | HTR1A (0.76) | HTR1AHTR2AHTR2CHTR2B | |
| SCHEMBL8812236 | 0.81 | HTR1A (0.76) | HTR1AHTR2AHTR2CHTR2B | |
| SCHEMBL3375158 | 0.81 | HTR1A (1.00) | HTR1A | |
| SCHEMBL8525515 | 0.81 | HTR1A (1.00) | HTR1A | |
| SCHEMBL8808266 | 0.78 | HTR1A (0.56) | HTR1AHTR2AHTR2CHTR2B | |
| SCHEMBL8808260 | 0.78 | HTR1A (0.56) | HTR1AHTR2AHTR2CHTR2B | |
| SCHEMBL8808092 | 0.74 | HTR1A (0.73) | HTR1AHTR2AHTR2CHTR2B | |
| SCHEMBL9080567 | 0.74 | HTR1A (1.00) | HTR1AHTR2AHTR2CHTR2B | |
| SCHEMBL9080563 | 0.74 | HTR1A (1.00) | HTR1AHTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0586525-B1 | CARBOXAMIDO-(1,2N)-CARBOCYCLIC-2-AMINOTETRALIN DERIVATIVES | UPJOHN CO (US) | 1997-04-16 | — | — | EP | claimed |
| EP-0586525-A1 | CARBOXAMIDO-(1,2N)-CARBOCYCLIC-2-AMINOTETRALIN DERIVATIVES. | UPJOHN CO (US) | 1994-03-16 | — | — | EP | claimed |