Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3376678 | 0.89 | KLK5 (0.46) | KLK5MTNR1AMTNR1BCYP2D6PPARA | |
| SCHEMBL19382648 | 0.83 | ATM (0.51) | MTNR1AMTNR1BCYP2D6PPARACTSS | |
| SCHEMBL7429081 | 0.82 | REN (0.49) | KLK5MTNR1AMTNR1B | |
| SCHEMBL8539590 | 0.82 | KLK5 (0.66) | KLK5CTSSATMCTSK | |
| SCHEMBL8538004 | 0.82 | KLK5 (0.66) | KLK5CTSSATMCTSK | |
| SCHEMBL6814907 | 0.82 | KLK5 (0.66) | KLK5CTSSATMCTSK | |
| SCHEMBL4972231 | 0.82 | KLK5 (0.66) | KLK5CTSSATMCTSK | |
| SCHEMBL6778243 | 0.82 | KLK5 (0.66) | KLK5CTSSATMCTSK | |
| SCHEMBL507001 | 0.80 | MTNR1A (0.66) | MTNR1AMTNR1BCYP2D6PPARACTSS | |
| SCHEMBL507002 | 0.80 | MTNR1A (0.66) | MTNR1AMTNR1BCYP2D6PPARACTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010107384-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-09-23 | — | — | WO | disclosed |
| WO-2010042030-A1 | ASPARTYL PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2010-04-15 | — | — | WO | disclosed |