SCHEMBL3375583

SCHEMBL3375583

CC(C)C(CC=O)NC(=O)OC(C)(C)C

nearest known ligand 0.67

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.67
CA2 P00918 2/20 0.67
CA7 P43166 2/20 0.67
CTSK P43235 12/20 0.55
CYP2D6 P10635 1/20 0.47
CA4 P22748 1/20 0.46
CA9 Q16790 1/20 0.46
CTSS P25774 4/20 0.45
CTSL P07711 2/20 0.40
CTSB P07858 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18055004 1.00 CA1 (0.67) CA1CA2CA7CTSKCYP2D6
SCHEMBL30859237 0.86 CA1 (0.54) CA1CA2CA7CTSKCYP2D6
SCHEMBL84426 0.86 CA1 (0.54) CA1CA2CA7CTSKCYP2D6
SCHEMBL73697 0.84 CTSK (0.53) CA1CA2CA7CTSKCYP2D6
SCHEMBL73696 0.84 CTSK (0.53) CA1CA2CA7CTSKCYP2D6
SCHEMBL75827 0.84 CTSK (0.53) CA1CA2CA7CTSKCYP2D6
SCHEMBL12507708 0.83 CA1 (0.51) CA1CA2CA7CTSKCYP2D6
SCHEMBL950335 0.83 CA1 (0.51) CA1CA2CA7CTSKCYP2D6
SCHEMBL19867870 0.83 CA1 (0.59) CA1CA2CA7CTSKCYP2D6
SCHEMBL3378599 0.82 CTSK (0.51) CA1CA2CA7CTSKCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
WO-2012000608-A2 NOVEL BETA-AMINOALDEHYDE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR CHEMICAL USE AS REACTIVE INTERMEDIATES GLUESENKAMP KARL-HEINZ (DE) 2012-01-05 WO disclosed