Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | CTSK | P43235 | 12/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | APLNR | P35414 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 3/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84426 | 1.00 | CA1 (0.54) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL18055004 | 0.86 | CA1 (0.67) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL3375583 | 0.86 | CA1 (0.67) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL11193697 | 0.85 | CA1 (0.49) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL26797154 | 0.82 | CA1 (0.56) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL26748563 | 0.82 | CA1 (0.56) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL73696 | 0.81 | CTSK (0.53) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL75827 | 0.81 | CTSK (0.53) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL73697 | 0.81 | CTSK (0.53) | CA1CA2CA7CTSKCYP2D6 | |
| SCHEMBL12507708 | 0.81 | CA1 (0.51) | CA1CA2CA7CTSKCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619037-A1 | SMALL MOLECULE-DRUG-CONJUGATES CLEAVABLE IN A TUMOR MICROENVIRONMENT | Lerchen, Hans-Georg (DE) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024105197-A1 | SMALL MOLECULE-DRUG-CONJUGATES CLEAVABLE IN A TUMOR MICROENVIRONMENT | VINCERX PHARMA GMBH (DE) | 2024-05-23 | — | — | WO | disclosed |