SCHEMBL337560

SCHEMBL337560

O=C(O)c1ccc(OCCOc2ccc(C(=O)O)cc2Cl)c(Cl)c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 6/20 0.58
TSHR P16473 1/20 0.57
NPC1 O15118 3/20 0.56
RAB9A P51151 3/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
HPGD P15428 1/20 0.56
POLB P06746 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
MEN1 O00255 1/20 0.54
LMNA P02545 1/20 0.54
GAA P10253 1/20 0.54
KMT2A Q03164 1/20 0.54
MCL1 Q07820 1/20 0.54
NFKB1 P19838 1/20 0.53
NFKB2 Q00653 1/20 0.53
RELA Q04206 1/20 0.53
TTR P02766 1/20 0.51
CASP6 P55212 1/20 0.51
RXRA P19793 1/20 0.51
RXRB P28702 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9623589 0.92 PKM (0.60) MRGPRX4TSHRNPC1RAB9ASMN1; SMN2
SCHEMBL9622885 0.92 PLAU (0.62) MRGPRX4TSHRNPC1RAB9ASMN1; SMN2
SCHEMBL13125267 0.92 MRGPRX4 (0.54) MRGPRX4NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL6131023 0.91 NPC1 (0.56) MRGPRX4TSHRNPC1RAB9ASMN1; SMN2
SCHEMBL18077305 0.90 NPC1 (0.55) MRGPRX4TSHRNPC1RAB9ASMN1; SMN2
SCHEMBL177169 0.90 THRA (0.56) MRGPRX4NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL566426 0.89 THRA (0.62) MRGPRX4TSHRNPC1RAB9ASMN1; SMN2
SCHEMBL566466 0.89 THRA (0.66) MRGPRX4TSHRNPC1RAB9ASMN1; SMN2
SCHEMBL9626608 0.87 THRA (0.68) TSHRHPGDTP53THRATHRB
SCHEMBL19815794 0.87 KDM4E (0.56) MRGPRX4NPC1RAB9ASMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4746721-A ENGINEERING PLASTICS KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1988-05-24 US claimed
JP-60188420-A None JP disclosed
JP-61002732-A None JP disclosed
JP-61002729-A None JP disclosed
JP-59041331-A None JP disclosed
JP-63223038-A None JP disclosed
JP-59167543-A None JP disclosed
JP-61197627-A None JP disclosed
JP-61081432-A None JP disclosed
JP-61073732-A None JP disclosed
US-4546030-A SUBJECTING FILM TO MULTISTAGE LONGITUDINAL, TRANSVERSE, AND BIAXIAL STRETCHING TORAY INDUSTRIES, INC. (JP) 1985-10-08 US disclosed
JP-S60188420-A HALOGEN-CONTAINING AROMATIC POLYESTER AGENCY OF IND SCIENCE & TECHNOL 1985-09-25 JP disclosed
JP-S60177021-A POLYAMIDE TORAY IND INC 1985-09-11 JP disclosed
US-4497865-A HIGH TENSILE STRENGTH MAGNETIC TAPES; SHRINKAGE INHIBITION TORAY INDUSTRIES, INC. (JP) 1985-02-05 US disclosed
JP-S59167543-A METHOD FOR PURIFYING DIALKYL 1,2-BIS(2-CHLOROPHENOXY) ETHANE-4,4'-DICARBOXYLATE TORAY IND INC 1984-09-21 JP disclosed
JP-S59124927-A PRODUCTION OF POLYESTER TORAY IND INC 1984-07-19 JP disclosed
JP-S59124926-A CRYSTALLINE COPOLYESTER TORAY IND INC 1984-07-19 JP disclosed
JP-S59124928-A PRODUCTION OF COPOLYESTER TORAY IND INC 1984-07-19 JP disclosed
JP-S5941331-A HALOGEN-CONTAINING AROMATIC POLYESTER AGENCY OF IND SCIENCE & TECHNOL 1984-03-07 JP disclosed
EP-0086302-A1 Polyethylene terephthalate film, process for the production thereof and magnetic recording medium therefrom TORAY INDUSTRIES, INC. (JP) 1983-08-24 EP disclosed