Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6684548 | 0.84 | TSHR (0.42) | TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11417940 | 0.82 | TSHR (0.56) | TSHRMEN1KMT2APTK2BKDM4E | |
| SCHEMBL27684159 | 0.82 | MEN1 (0.50) | MEN1KMT2AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL11973136 | 0.80 | MAPT (0.53) | MEN1KMT2AKDM4ECYP1A2CYP2C19 | |
| SCHEMBL2318350 | 0.78 | PTGS1 (0.61) | TSHRMEN1KMT2APTK2BKDM4E | |
| SCHEMBL1645161 | 0.78 | TSHR (0.53) | TSHRMEN1KMT2APTK2BKDM4E | |
| SCHEMBL27182739 | 0.77 | KMT2A (0.56) | TSHRMEN1KMT2APTK2BKDM4E | |
| Sulfuric Acid SCHEMBL8791976 | 0.77 | KDM4E (0.48) | TSHRMEN1KMT2APTK2BKDM4E | |
| SCHEMBL1075937 | 0.76 | GAA (0.55) | MEN1KMT2AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL7008643 | 0.76 | ALDH1A1 (0.39) | MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809267-B2 | Antiviral compounds | GILEAD SCIENCES, INC. (US) | 2014-08-19 | — | — | US | disclosed |
| US-20140051626-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2014-02-20 | — | — | US | disclosed |
| US-8513186-B2 | Antiviral compounds | GILEAD SCIENCES, INC. (US) | 2013-08-20 | — | — | US | disclosed |
| CN-101801925-A | antiviral compounds | GILEAD SCIENCES INC | 2010-08-11 | — | — | CN | disclosed |
| EP-2162432-A2 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2010-03-17 | — | — | EP | disclosed |
| WO-2010017405-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2010-02-11 | — | — | WO | disclosed |
| US-20090186869-A1 | Antiviral compounds | GILEAD SCIENCES, INC. (US) | 2009-07-23 | — | — | US | disclosed |
| WO-2009005677-A2 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2009-01-08 | — | — | WO | disclosed |
| EP-0970148-B1 | OLIGOMERIC AZO DYES | BASF AG (DE) | 2001-06-13 | — | — | EP | disclosed |
| US-6114512-A | REACTING A TETRAZOTIZED DIAMINE COMPOUND WITH A COUPLING COMPOUND CONTAINING AMINONAPHTHOL-MONO OR DI-SULFONIC ACID COMPOUND TO FORM TETRAAZO DYE | BASF AKTIENGESELLSCHAFT (DE) | 2000-09-05 | — | — | US | disclosed |
| EP-0970148-A1 | OLIGOMERIC AZO DYES | BASF AKTIENGESELLSCHAFT (DE) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998041581-A1 | OLIGOMERIC AZO DYES | BASF AKTIENGESELLSCHAFT (DE) | 1998-09-24 | — | — | WO | disclosed |
| EP-0136142-B1 | THERMALLY DEVELOPABLE, LIGHT-SENSITIVE MATERIAL | KONICA CORPORATION (JP) | 1990-04-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090186869-A1 | Antiviral compounds | MAVS, EIF2AK2, ZC3HAV1 | TSHR 4853/4885MEN1 4292/4885KMT2A 3803/4885 |
| US-20140051626-A1 | ANTIVIRAL COMPOUNDS | MAVS, EIF2AK2, ZC3HAV1 | TSHR 4853/4885MEN1 4292/4885KMT2A 3803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.