Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22749514 | 0.90 | KDM4E (0.50) | CNR2KDM4ETSHRMAPK1HRH3 | |
| SCHEMBL8064154 | 0.86 | HRH3 (0.60) | CNR2KDM4ETSHRMAPK1HRH3 | |
| Ethylene SCHEMBL28212464 | 0.86 | HRH3 (0.60) | CNR2KDM4ETSHRMAPK1HRH3 | |
| SCHEMBL375111 | 0.86 | KDM4E (0.68) | CNR2KDM4ETSHRMAPK1HRH3 | |
| SCHEMBL479294 | 0.86 | TSHR (0.50) | CNR2KDM4ETSHRMAPK1SLC6A2 | |
| SCHEMBL81248 | 0.86 | HRH3 (0.65) | CNR2KDM4ETSHRMAPK1HRH3 | |
| SCHEMBL11501764 | 0.86 | TSHR (0.50) | CNR2KDM4ETSHRMAPK1SLC6A2 | |
| Fluoride SCHEMBL11307410 | 0.84 | HRH3 (0.62) | CNR2KDM4ETSHRMAPK1HRH3 | |
| Water SCHEMBL5507580 | 0.84 | HRH3 (0.62) | CNR2KDM4ETSHRMAPK1HRH3 | |
| Iodide SCHEMBL21693881 | 0.84 | HRH3 (0.62) | CNR2KDM4ETSHRMAPK1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229057-B1 | Organosol and liquid inks comprising the same | SAMSUNG ELECTRONICS CO LTD (KR) | 2007-05-23 | — | — | EP | claimed |
| WO-2013066469-A2 | KINASE INHIBITORS CAPABLE OF INCREASING THE SENSITIVITY OF BACTERIAL PATHOGENS TO B-LACTAM ANTIBIOTICS | SEATTLE CHILDREN'S RESEARCH INSTITUTE (US) | 2013-05-10 | — | — | WO | disclosed |
| US-20100324091-A1 | Pyrazolone Derivative | KOWA COMPANY, LTD. (JP) | 2010-12-23 | — | — | US | disclosed |
| EP-2172458-A1 | PYRAZOLONE DERIVATIVE | Kowa Company, Ltd. (JP) | 2010-04-07 | — | — | EP | disclosed |
| WO-2005118584-A2 | SAFRAMYCIN ANALOGS AS THERAPEUTIC AGENTS IN THE TREATMENT OF CANCER | AXYS PHARMACEUTICALS, INC. (US) | 2005-12-15 | — | — | WO | disclosed |
| CN-1057674-C | Growth promoting composition and production thereof | KITASATO INST (JP) | 2000-10-25 | — | — | CN | disclosed |
| US-5854407-A | 15-hydroxy 6,9-hemiacetal erythromycin compounds | TAKEDA CHEMICAL CORPORATION (JP) | 1998-12-29 | — | — | US | disclosed |
| US-5724629-A | Liquid developer monitoring device, liquid developer controlling system, and image forming apparatus using same | MINOLTA CO., LTD. (JP) | 1998-03-03 | — | — | US | disclosed |
| US-5689779-A | Liquid developer and developing method and developing apparatus using same | MINOLTA CO., LTD. (JP) | 1997-11-18 | — | — | US | disclosed |
| EP-0625507-B1 | Urea derivatives and their use as acat inhibitors | NISSHIN FLOUR MILLING CO (JP) | 1997-07-23 | — | — | EP | disclosed |
| US-4760147-A | Isopropyl 1,4-dihydro-2,6-dimethyl-4-(2,3-dichlorophenyl)-3-(1,3,4-oxadiazol-2 -yl)pyridine-5-carboxylate | CASSELLA AKTIENGESELLSCHAFT (DE) | 1988-07-26 | — | — | US | disclosed |
| CN-86106828-A | DIGESTIVE TRACT CONTRACTILE MOTION STIMULANT | — | 1987-04-08 | — | — | CN | disclosed |
| EP-0215355-A2 | Erythromycin derivative and process for preparing the same | KITASATO KENKYUSHO (JP) | 1987-03-25 | — | — | EP | disclosed |
| EP-0213617-A2 | Digestive tract contractile motion stimulant | KITASATO KENKYUSHO (JP) | 1987-03-11 | — | — | EP | disclosed |
| EP-0177122-A2 | Acrylamide derivatives | Nippon Paint Co., Ltd. (JP) | 1986-04-09 | — | — | EP | disclosed |
| EP-0172509-A2 | Process for the preparation of optically active, substituted 1,4-dihydropyridines and their use as medicaments | CASSELLA Aktiengesellschaft (DE) | 1986-02-26 | — | — | EP | disclosed |
| US-4558058-A | HYPOTENSIVE AGENTS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1985-12-10 | — | — | US | disclosed |
| US-4495192-A | HYPOTENSIVE AGENTS; VASODILATORS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1985-01-22 | — | — | US | disclosed |
| EP-0116708-A1 | Substituted 1,4-dihydropyridines, method for their preparation and their use as pharmaceuticals | CASSELLA Aktiengesellschaft (DE) | 1984-08-29 | — | — | EP | disclosed |
| EP-0093945-A2 | 1,4-Dihydropyridine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1983-11-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324091-A1 | Pyrazolone Derivative | SERPINE1, SERPINC1, TFPI | CNR2 2433/4885KDM4E 4172/4885TSHR 1622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.