Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3377281 | 0.93 | CA12 (0.43) | TSHRHTTCA12CA9SMN1; SMN2 | |
| SCHEMBL3376166 | 0.90 | TSHR (0.54) | TSHRHTTHPGDCYP2C9SMN1; SMN2 | |
| SCHEMBL3373263 | 0.90 | TSHR (0.50) | TSHRHTTHPGDCYP2C9CA12 | |
| SCHEMBL5716640 | 0.88 | HCRTR1 (0.40) | TSHRHTTHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL3378263 | 0.87 | TSHR (0.47) | TSHRHTTHPGDCYP2C9CA12 | |
| SCHEMBL3375836 | 0.85 | ALDH1A1 (0.42) | HPGDSMN1; SMN2ALDH1A1HCRTR1MEN1 | |
| SCHEMBL3377448 | 0.84 | MEN1 (0.41) | HPGDSMN1; SMN2ALDH1A1HCRTR1MEN1 | |
| SCHEMBL3378393 | 0.82 | CA12 (0.43) | TSHRHTTCA12CA9SMN1; SMN2 | |
| SCHEMBL3377283 | 0.82 | HCRTR1 (0.45) | TSHRHTTHPGDCA12CA9 | |
| SCHEMBL3377862 | 0.81 | POLB (0.45) | HPGDSMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517886-B1 | NOVEL PHTHALAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-11-10 | — | — | EP | disclosed |
| CN-100556903-C | Phthalic acid derivative and as the purposes of preparation butyl benzene orthobenzol diacid amide derivative intermediate | BAYER CROPSCIENCE AG (DE) | 2009-11-04 | — | — | CN | disclosed |
| CN-100516033-C | Novel phthalamide derivatives | BAYER CROPSCIENCE AG (DE) | 2009-07-22 | — | — | CN | disclosed |
| CN-1955172-A | Phthalic acid derivative and use for preparing phthalamide derivative intermediate | BAYER CROPSCIENCE AG (DE) | 2007-05-02 | — | — | CN | disclosed |
| CN-1955162-A | Phthalic acid derivative and use for preparing phthalamide derivative intermediate | BAYER CROPSCIENCE AG (DE) | 2007-05-02 | — | — | CN | disclosed |
| US-7132455-B2 | Phthalamide derivatives | BAYER CROPSCIENCE AG (DE) | 2006-11-07 | — | — | US | disclosed |
| US-20060035967-A1 | Novel phthalamide derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2006-02-16 | — | — | US | disclosed |
| CN-1671655-A | Novel phthalamide derivatives | BAYER CROPSCIENCE AG (DE) | 2005-09-21 | — | — | CN | disclosed |
| EP-1517886-A1 | NOVEL PHTHALAMIDE DERIVATIVES | Bayer CropScience AG (DE) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000796-A1 | NOVEL PHTHALAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2003-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060035967-A1 | Novel phthalamide derivatives | HDAC1, HDAC2, CRY1 | TSHR 2448/4885HTT 513/4885HPGD 2293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.