SCHEMBL3376167

SCHEMBL3376167

CCCCCCCC[Si](C)(C)c1ccccc1CBr

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.38
KCNH2 Q12809 2/20 0.37
CNR1 P21554 3/20 0.33
CNR2 P34972 3/20 0.33
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
FAAH O00519 1/20 0.32
MGLL Q99685 1/20 0.32
NR1H2 P55055 1/20 0.32
NR1H3 Q13133 1/20 0.32
NAAA Q02083 1/20 0.32
SLC9A1 P19634 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21195795 0.83 CYP1A2 (0.33) LMNA
SCHEMBL556905 0.81 LIPG (0.39) LIPGKCNH2CNR1CNR2NR1H2
SCHEMBL6422759 0.81 CNR1 (0.38) KCNH2CNR1CNR2
SCHEMBL6424294 0.81 CNR1 (0.38) KCNH2CNR1CNR2
SCHEMBL5703510 0.81 CNR1 (0.38) KCNH2CNR1CNR2
SCHEMBL6425496 0.81 CNR1 (0.38) KCNH2CNR1CNR2
SCHEMBL6424744 0.80 CNR1 (0.33) KCNH2CNR1CNR2KDM4ELMNA
SCHEMBL1447561 0.80 CNR1 (0.33) KCNH2CNR1CNR2KDM4ELMNA
SCHEMBL18796184 0.76 CYP1A2 (0.41) KCNH2CNR1CNR2KDM4EHTT
SCHEMBL18796151 0.76 CYP1A2 (0.41) KCNH2CNR1CNR2KDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1116768-B1 Polymeric fluorescent substance and polymer light-emitting device SUMITOMO CHEMICAL CO (JP) 2010-11-03 EP disclosed
US-7256245-B2 Polymeric fluorescent substance and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-08-14 US disclosed
US-20030212247-A1 Polymeric fluorescent substance and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED 2003-11-13 US disclosed
US-6602969-B2 Liquid crystal display SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-08-05 US disclosed
US-20010020085-A1 Polymeric fluorescent substance and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-09-06 US disclosed
EP-1116768-A2 Polymeric fluorescent substance and polymer light-emitting device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-18 EP disclosed