SCHEMBL6424744

SCHEMBL6424744

CCCCCCCCCC[Si](C)(C)c1cc(CBr)ccc1CBr

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 4/20 0.33
CNR2 P34972 4/20 0.33
HPGD P15428 1/20 0.32
TP53 P04637 2/20 0.31
CYP3A4 P08684 2/20 0.31
MEN1 O00255 1/20 0.31
ALOX5 P09917 1/20 0.31
MAPT P10636 1/20 0.31
TYR P14679 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ESR1 P03372 2/20 0.31
ADRA2A P08913 2/20 0.31
ADORA3 P0DMS8 2/20 0.31
TACR2 P21452 2/20 0.31
SLC6A2 P23975 2/20 0.31
SLC6A4 P31645 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1447561 1.00 CNR1 (0.33) CNR1CNR2HPGDTP53CYP3A4
SCHEMBL6424294 0.84 CNR1 (0.38) CNR1CNR2KCNH2
SCHEMBL6425496 0.84 CNR1 (0.38) CNR1CNR2KCNH2
SCHEMBL6422759 0.84 CNR1 (0.38) CNR1CNR2KCNH2
SCHEMBL5703510 0.84 CNR1 (0.38) CNR1CNR2KCNH2
SCHEMBL3376167 0.80 LIPG (0.38) CNR1CNR2HTTKDM4ELMNA
SCHEMBL6424764 0.77 CNR1 (0.35) CNR1CNR2
SCHEMBL7456717 0.75 CNR1 (0.36) CNR1CNR2KCNH2
SCHEMBL8612702 0.75 TRPA1 (0.31) TSHRALDH1A1
SCHEMBL5703516 0.73 POLB (0.39) CNR1CNR2MEN1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6885038-B2 Light-emitting polymers and polymer light-emitting diodes AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2005-04-26 US disclosed
US-20030088043-A1 Light-emitting polymers and polymer light-emitting diodes AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2003-05-08 US disclosed