SCHEMBL3376258

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3378969	0.87	DPP7 (0.52)	PPARAALDH1A1KMT2ANTRK1
	SCHEMBL3379922	0.86	GRM5 (0.60)	PPARAALDH1A1NTRK1
	SCHEMBL3378131	0.85	PPARA (0.53)	PPARAMAPTKMT2AHSD11B1MAPK8
	SCHEMBL3415407	0.84	HSD11B1 (0.45)	PPARAALDH1A1MAPTL3MBTL1KMT2A
	SCHEMBL3377905	0.84	PPARA (0.49)	PPARAKMT2ANTRK1MEN1SMN1; SMN2
	SCHEMBL3259882	0.81	ALDH1A1 (0.70)	ALDH1A1MAPTL3MBTL1KMT2AHSD11B1
	SCHEMBL2188996	0.80	PPARA (0.79)	PPARAALDH1A1KMT2AMEN1RAB9A
	SCHEMBL3376257	0.80	HTT (0.65)	ALDH1A1KMT2AHSD11B1TSHRMEN1
	SCHEMBL3379277	0.78	ALDH1A1 (0.60)	ALDH1A1L3MBTL1TSHRNTRK1RAB9A
	SCHEMBL27308605	0.77	NPC1 (0.75)	ALDH1A1MAPTKMT2ATSHRRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.