Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21550880 | 0.97 | TSHR (0.38) | ALDH1A1TSHRTDP1 | |
| SCHEMBL5446851 | 0.82 | TSHR (0.55) | ALDH1A1TSHRTDP1 | |
| SCHEMBL8967283 | 0.82 | ALDH1A1 (0.32) | ALDH1A1TSHR | |
| SCHEMBL15012906 | 0.78 | — | — | |
| SCHEMBL15012663 | 0.78 | — | — | |
| SCHEMBL8967202 | 0.76 | TSHR (0.48) | ALDH1A1TSHRTDP1 | |
| SCHEMBL24289146 | 0.75 | — | — | |
| SCHEMBL3032918 | 0.72 | — | — | |
| SCHEMBL688308 | 0.71 | — | — | |
| SCHEMBL4002197 | 0.71 | TSHR (0.67) | ALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773940-B2 | PROCESS FOR SYNTHESIS OF SUBSTITUTED SULPHOXIDES | ASTRAZENECA AB (SE) | 2010-11-17 | — | — | EP | disclosed |
| EP-0773940-B1 | PROCESS FOR SYNTHESIS OF SUBSTITUTED SULPHOXIDES | ASTRAZENECA AB (SE) | 2003-06-04 | — | — | EP | disclosed |
| US-5948789-A | ASYMMETRIC OXIDATION OF A PRO-CHIRAL SULPHIDE TO THE SINGLE ENANTIOMERS OR AN ENANTIOMERICALLY ENRICHED FORM OF THE CORRESPONDING SULPHOXIDE. OPTICALLY PURE SUBSTITUTED 2-(2-PYRIDINYLMETHYL-SULPHINYL)-1H-BENZIMIDAZOLES. | ASTRA AKTIEBOLAG (SE) | 1999-09-07 | — | — | US | disclosed |
| EP-0773940-A1 | PROCESS FOR SYNTHESIS OF SUBSTITUTED SULPHOXIDES | Astra Aktiebolag (SE) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996002535-A1 | PROCESS FOR SYNTHESIS OF SUBSTITUTED SULPHOXIDES | ASTRA AKTIEBOLAG (SE) | 1996-02-01 | — | — | WO | disclosed |