Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8967194 | 0.91 | — | — | |
| SCHEMBL3376449 | 0.82 | ALDH1A1 (0.38) | ALDH1A1TSHR | |
| SCHEMBL11030115 | 0.80 | LMNA (0.43) | — | |
| SCHEMBL21550880 | 0.79 | TSHR (0.38) | ALDH1A1TSHR | |
| SCHEMBL230996 | 0.79 | CA1 (0.33) | ALDH1A1 | |
| Alcohol SCHEMBL28425846 | 0.72 | LMNA (0.37) | — | |
| SCHEMBL23931188 | 0.71 | LMNA (0.50) | ALDH1A1TSHR | |
| SCHEMBL9695892 | 0.71 | LMNA (0.50) | ALDH1A1TSHR | |
| SCHEMBL4532996 | 0.71 | LMNA (0.50) | ALDH1A1TSHR | |
| SCHEMBL6523739 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468434-B1 | Novel piperidyl ethers and thioethers as inhibitors of cholesterol biosynthesis | MERRELL DOW PHARMA (US) | 1996-02-28 | — | — | EP | disclosed |
| US-5348964-A | Anticholesterol agents or fungicides | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-09-20 | — | — | US | disclosed |
| EP-0468434-A1 | Novel piperidyl ethers and thioethers as inhibitors of cholesterol biosynthesis | MERRELL PHARMACEUTICALS INC. (US) | 1992-01-29 | — | — | EP | disclosed |