Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL723652 | 0.96 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL16267281 | 0.93 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL16267272 | 0.93 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL8893978 | 0.93 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL16267701 | 0.93 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL2096964 | 0.84 | — | — | |
| SCHEMBL4273964 | 0.82 | — | — | |
| SCHEMBL8811539 | 0.82 | — | — | |
| SCHEMBL10583089 | 0.82 | — | — | |
| SCHEMBL13316781 | 0.82 | MAPK1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012083261-A1 | BLOOD BRAIN BARRIER-PENETRATING OXIMES FOR CHOLISTENERASES REACTIVATION | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2012-06-21 | — | — | WO | claimed |
| EP-3122754-A2 | USE OF THE FL118 CORE CHEMICAL STRUCTURE PLATFORM TO GENERATE FL118 DERIVATIVES FOR TREATMENT OF HUMAN DISEASE | Canget Biotekpharma, LLC (US) | 2017-02-01 | — | — | EP | disclosed |
| WO-2015148415-A2 | USE OF THE FL118 CORE CHEMICAL STRUCTURE PLATFORM TO GENERATE FL118 DERIVATIVES FOR TREATMENT OF HUMAN DISEASE | CANGET BIOTEKPHARMA, LLC (US) | 2015-10-01 | — | — | WO | disclosed |
| WO-2012083261-A1 | BLOOD BRAIN BARRIER-PENETRATING OXIMES FOR CHOLISTENERASES REACTIVATION | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2012-06-21 | — | — | WO | disclosed |
| WO-2010042642-A1 | CALCIUM RECEPTOR MODULATING AGENTS | AMGEN INC. (US) | 2010-04-15 | — | — | WO | disclosed |