⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL723652 | 0.87 | ALDH1A1 (0.38) | — | |
| SCHEMBL8893978 | 0.84 | ALDH1A1 (0.36) | — | |
| SCHEMBL16267272 | 0.84 | ALDH1A1 (0.36) | — | |
| SCHEMBL3376457 | 0.84 | ALDH1A1 (0.36) | — | |
| SCHEMBL43710 | 0.84 | — | — | |
| SCHEMBL16267281 | 0.84 | ALDH1A1 (0.36) | — | |
| SCHEMBL16267701 | 0.84 | ALDH1A1 (0.36) | — | |
| Ether SCHEMBL10662710 | 0.81 | LMNA (0.35) | — | |
| Ether SCHEMBL10744108 | 0.81 | LMNA (0.35) | — | |
| Fluoride SCHEMBL27566532 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9310682-B2 | Positive-type resist composition | CENTRAL GLASS COMPANY, LIMITED (JP) | 2016-04-12 | — | — | US | disclosed |
| US-9310682-B2 | Positive-type resist composition | CENTRAL GLASS COMPANY, LIMITED (JP) | 2016-04-12 | — | — | US | disclosed |
| CN-104105787-A | Laundry care compositions containing dyes | MILLIKEN & AMP | 2014-10-15 | — | — | CN | disclosed |
| US-8785694-B2 | Processes for the preparation of di-(2-aminoethyl) formal, di-(3-aminopropyl) formal, and related molecules | Connora Technologies, Inc (US) | 2014-07-22 | — | — | US | disclosed |
| US-20140134542-A1 | Positive-Type Resist Composition | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-05-15 | — | — | US | disclosed |
| US-20140134542-A1 | Positive-Type Resist Composition | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-05-15 | — | — | US | disclosed |
| US-20130131052-A1 | Amelioration Of The Development Of Cataracts And Other Ophthalmic Diseases | MATIER WILLIAM L (US) | 2013-05-23 | — | — | US | disclosed |
| US-8163753-B2 | 2-(4-(4-(4-chlorophenyl)oxazol-2-yl)phenoxymethyl)-2-methyl-6-nitro-2,3-dihydroimidazo[2,1-b]oxazole; bactericide; excellent bactericidal action against Mycobacterium tuberculosis, multi-drug-resistant Mycobacterium tuberculosis, and atypical acid-fast bacteria | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | OTSUKA PHAMACEUTICAL CO., LTD. (JP) | 2008-05-22 | — | — | US | disclosed |
| US-4785133-A | Process for the preparation of alkyl 3-alkoxypropionates | EASTMAN KODAK COMPANY (US) | 1988-11-15 | — | — | US | disclosed |