SCHEMBL3376531

SCHEMBL3376531

ClCCOCCOC1CCCCO1

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
KDM4C Q9H3R0 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5551638 1.00 MEN1 (0.40) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL6714850 0.91 MEN1 (0.44) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL13455405 0.91 MEN1 (0.44) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL319842 0.89 MEN1 (0.43) MEN1KMT2AKDM4CL3MBTL1NPC1
Magnesium SCHEMBL30504225 0.87 MEN1 (0.42) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL28428308 0.87 MEN1 (0.42) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL6503220 0.85 MEN1 (0.36) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL13455407 0.85 MEN1 (0.39) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL23544814 0.82 MEN1 (0.46) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL21169155 0.82 MEN1 (0.43) MEN1KMT2AKDM4CL3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12398121-B2 Anti-cancer nuclear hormone receptor-targeting compounds NUVATION BIO INC. (US) 2025-08-26 US disclosed
EP-3789472-B1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION FOR OPTICAL ELEMENT, POLYMER, OPTICALLY ANISOTROPIC BODY, AND OPTICAL ELEMENT FOR DISPLAY DEVICE LG CHEMICAL LTD (KR) 2025-04-16 EP disclosed
US-20250034143-A1 SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF HYDRA BIOSCIENCES, LLC (US) 2025-01-30 US disclosed
US-11958854-B2 Substituted xanthines and methods of use thereof HYDRA BIOSCIENCES, LLC (US) 2024-04-16 US disclosed
CN-111989384-B Polymerizable liquid crystal compound, liquid crystal composition for optical element, polymer, optically anisotropic body, and optical element for display device 株式会社LG化学 2023-09-08 CN disclosed
US-11674082-B2 Polymerizable liquid crystal compound, liquid crystal composition for optical element, polymer, optically anisotropic body, and optical element for display device LG CHEM, LTD. 2023-06-13 US disclosed
US-20230122310-A1 ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS SAGARD HOLDINGS MANAGER LP, AS ADMINISTRATIVE AGENT (CA) 2023-04-20 US disclosed
US-20230122310-A1 ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS SAGARD HOLDINGS MANAGER LP, AS ADMINISTRATIVE AGENT (CA) 2023-04-20 US disclosed
US-20230040259-A1 SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF HYDRA BIOSCIENCES, LLC (US) 2023-02-09 US disclosed
US-20230040259-A1 SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF HYDRA BIOSCIENCES, LLC (US) 2023-02-09 US disclosed
EP-0585314-A1 NOVEL HETEROCYCLIC CARBOXYLIC ACIDS. NOVO NORDISK AS (DK) 1994-03-09 EP disclosed
WO-1993013089-A1 MACROCYCLIC POLYETHER CARBOXYLIC ACIDS URBAN FRANK J (US) 1993-07-08 WO disclosed
EP-0494925-A4 POLYMERIZABLE (FUNCTIONALLY-SUBSTITUTED PHENYLENE) SEMI-RIGID CROWNS 1993-01-20 EP disclosed
WO-1992020658-A1 NOVEL HETEROCYCLIC CARBOXYLIC ACIDS NOVO NORDISK A/S (DK) 1992-11-26 WO disclosed
US-5142068-A MONO- AND DI(FUNCTIONALLY-SUBSTITUTED PHENYLENE) SEMI-RIGID CROWNS AND PROCESSES FOR MAKING VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 1992-08-25 US disclosed
EP-0494925-A1 POLYMERIZABLE (FUNCTIONALLY-SUBSTITUTED PHENYLENE) SEMI-RIGID CROWNS VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 1992-07-22 EP disclosed
WO-1991004971-A1 POLYMERIZABLE (FUNCTIONALLY-SUBSTITUTED PHENYLENE) SEMI-RIGID CROWNS VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 1991-04-18 WO disclosed
US-4935442-A Tetrahydrofuran-containing macrocyclic polyether carboxylic acids PFIZER INC. (US) 1990-06-19 US disclosed
US-4876367-A ANIMAL GROWTH REGULATORS PFIZER INC. (US) 1989-10-24 US disclosed
US-4777270-A INCREASE EFFICIENCY OF FEED UTILIZATION IN RUMINANTS PFIZER INC. (US) 1988-10-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12398121-B2 Anti-cancer nuclear hormone receptor-targeting compounds NCOA1, NCOR1, NCOA3 MEN1 2250/4885KMT2A 2014/4885KDM4C 2613/4885
US-11958854-B2 Substituted xanthines and methods of use thereof TRPC5, TRPC7, TRPC4 MEN1 2331/4885KMT2A 4201/4885KDM4C 2391/4885
US-20230040259-A1 SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF TRPC5, TRPC7, TRPC4 MEN1 2331/4885KMT2A 4201/4885KDM4C 2391/4885
US-20230122310-A1 ANTI-CANCER NUCLEAR HORMONE RECEPTOR-TARGETING COMPOUNDS NCOA1, NCOR1, NCOA3 MEN1 2250/4885KMT2A 2014/4885KDM4C 2613/4885
US-20250034143-A1 SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF TRPC5, TRPC7, TRPC4 MEN1 2331/4885KMT2A 4201/4885KDM4C 2391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.