Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27283527 | 0.98 | ESR1 (0.53) | ESR1TSHRMAPK1KMT2AHSD17B10 | |
| SCHEMBL7213233 | 0.81 | ESR1 (0.59) | ESR1TSHRMAPK1KMT2AHSD17B10 | |
| SCHEMBL11553294 | 0.81 | ESR1 (0.56) | ESR1TSHRMAPK1KMT2AHSD17B10 | |
| SCHEMBL17333643 | 0.81 | ESR1 (0.56) | ESR1TSHRMAPK1KMT2AHSD17B10 | |
| SCHEMBL4554082 | 0.81 | TSHR (0.56) | ESR1TSHRMAPK1KMT2AHSD17B10 | |
| SCHEMBL27996134 | 0.80 | TSHR (0.45) | ESR1TSHRMAPK1KMT2AHSD17B10 | |
| SCHEMBL6403369 | 0.80 | ESR1 (0.54) | ESR1TSHRMAPK1KMT2AHSD17B10 | |
| SCHEMBL5892163 | 0.79 | ESR1 (0.59) | ESR1TSHRMAPK1KMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL6640412 | 0.79 | TSHR (0.54) | ESR1TSHRMAPK1KMT2AHSD17B10 | |
| SCHEMBL6017430 | 0.79 | ESR1 (0.59) | ESR1TSHRMAPK1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996544-B1 | A METHOD OF PREPARATION OF (R)-(-)-5(2-AMINOPROPYL)-2-METHOXYBENZENESULFONAMIDE | ZENTIVA KS (CZ) | 2010-11-10 | — | — | EP | disclosed |
| US-7638649-B2 | Method of preparation of (R)-(−)-5-(2-aminopropyl)-2-methoxybenzenesulfonamide | ZENTIVA, K.S. (CZ) | 2009-12-29 | — | — | US | disclosed |
| US-20080319225-A1 | Method of Preparation of (R)-(-)-5(2-Aminopropyl)-2-Methoxybenzenesulfonamide | ZENTIVA, A.S. (CZ) | 2008-12-25 | — | — | US | disclosed |
| EP-1996544-A1 | A METHOD OF PREPARATION OF (R)-(-)-5(2-AMINOPROPYL)-2-METHOXYBENZENESULFONAMIDE | Zentiva, a.s. (CZ) | 2008-12-03 | — | — | EP | disclosed |
| WO-2005075415-A1 | A METHOD OF PREPARATION OF (R)-(-)-5(2-AMINOPROPYL)-2-METHOXYBENZENESULFONAMIDE | ZENTIVA, A.S. (CZ) | 2005-08-18 | — | — | WO | disclosed |
| WO-2003035608-A1 | A METHOD OF THE PREPARATION OF (R)-(-)-5`2-`2-(2-ETHOXYPHENOXY) ETHYLAMINO! PROPYL!-2-METHOXYBENZENESULPHONAMIDE (TAMSULOSIN) | LECIVA, A.S. (CZ) | 2003-05-01 | — | — | WO | disclosed |
| EP-0276319-B1 | SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL | FUJI PHOTO FILM CO LTD (JP) | 1994-10-05 | — | — | EP | disclosed |
| EP-0304067-B1 | Silver halide color photographic light-sensitive material containing epoxy compound | FUJI PHOTO FILM CO LTD (JP) | 1993-11-10 | — | — | EP | disclosed |
| US-5183731-A | Storage stability yellow images; heat and water resistant, colorfastness | FUJI PHOTO FILM CO., LTD. (JP) | 1993-02-02 | — | — | US | disclosed |
| CN-1015054-B | N-INDOLYLETHYL SULPHONIC ACID AMIDES, PROCESS FOR PREPARATION THEREOF AND THEIR USE | BAYER AG (DE) | 1991-12-11 | — | — | CN | disclosed |
| US-5055386-A | Excellent image storing properties | FUJI PHOTO FILM CO., LTD. (JP) | 1991-10-08 | — | — | US | disclosed |
| US-5006453-A | With specific oil soluble coupler, solvent, polymer having no acid groups | FUJI PHOTO FILM CO. LTD. (JP) | 1991-04-09 | — | — | US | disclosed |
| US-4962014-A | USING SULFITE CONTAINING BLIXING LIQUID TO SHORTEN TIME AND REDUCE WATER CONSUMPTION WITHOUT IMPAIRING STORAGE STABILITY | FUJI PHOTO FILM CO., LTD. (JP) | 1990-10-09 | — | — | US | disclosed |
| US-4914007-A | REDUCING THE WATER WASHING TIME OF CONTINUOUS COLOR DEVELOPMENT | FUJI PHOTO FILM CO., LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| EP-0304067-A2 | Silver halide color photographic light-sensitive material containing epoxy compound | Fuji Photo Film Co., Ltd. (JP) | 1989-02-22 | — | — | EP | disclosed |
| EP-0276319-A1 | SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1988-08-03 | — | — | EP | disclosed |
| CN-86102761-A | N-indyl ethyl-sulfonamides Preparation Method And The Use | — | 1987-02-25 | — | — | CN | disclosed |
| US-4588677-A | 4-MERCAPTO-5-PYRAZOLONE TYPE MAGENTA COUPLERS | FUJI PHOTO FILM CO., LTD. (JP) | 1986-05-13 | — | — | US | disclosed |
| US-4584266-A | 2-EQUIVALENT 5-PYRAZOLONE MAGENTA COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1986-04-22 | — | — | US | disclosed |
| US-4556630-A | NOVEL MAGENTA COUPLERS HAVING ARYLTHIO GROUP AT THE COUPLING ACTIVE POSITION OF A PYRAZOLONE | FUJI PHOTO FILM CO., LTD. (JP) | 1985-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080319225-A1 | Method of Preparation of (R)-(-)-5(2-Aminopropyl)-2-Methoxybenzenesulfonamide | NPSR1, TPSAB1, TPSB2 | ESR1 2733/4885TSHR 501/4885MAPK1 1923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.