Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRB | P28702 | 3/20 | 0.64 |
| ▸ | RXRA | P19793 | 2/20 | 0.64 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.50 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | ACLY | P53396 | 1/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.45 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14089899 | 0.89 | RXRB (0.79) | RXRBRXRACYP2C8KDM4EALDH1A1 | |
| SCHEMBL424990 | 0.84 | RXRB (0.70) | RXRBRXRAKDM4EALDH1A1HPGD | |
| SCHEMBL6488781 | 0.83 | RXRA (0.54) | RXRBRXRACYP2C8KDM4EALDH1A1 | |
| Hydrogen Sulfide SCHEMBL27780391 | 0.82 | RXRB (0.68) | RXRBRXRAKDM4EALDH1A1HPGD | |
| SCHEMBL8840571 | 0.80 | MCL1 (0.65) | RXRBRXRAALDH1A1MCL1SMN1; SMN2 | |
| SCHEMBL23354125 | 0.80 | RXRA (0.54) | RXRBRXRACYP2C8KDM4EALDH1A1 | |
| SCHEMBL29978858 | 0.80 | RXRA (0.54) | RXRBRXRACYP2C8KDM4EALDH1A1 | |
| SCHEMBL6491531 | 0.80 | CYP2C8 (0.56) | RXRBRXRACYP2C8KDM4EALDH1A1 | |
| SCHEMBL30679777 | 0.80 | CSNK2A1 (0.59) | RXRBRXRAKDM4EALDH1A1MCL1 | |
| SCHEMBL107259 | 0.80 | CSNK2A1 (0.59) | RXRBRXRAKDM4EALDH1A1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1907860-B1 | MASS LABELS | ELECTROPHORETICS LTD (GB) | 2010-11-17 | — | — | EP | disclosed |
| EP-1907860-A2 | MASS LABELS | Electrophoretics Limited (GB) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007012849-A2 | MASS LABELS FOR BIOMOLECULES CONTAINING A 2,6-DIMETHYL-PIPERIDIN-l-YL METHYLENE OR A PYRIMIDIN-2-YL THIOMETHYLENE MASS MARKER MOIETY AND A SUCCINIMID-OXY-CARBONYL REACTIVE FUNCTIONAL GROUP | ELECTROPHORETICS LIMITED (GB) | 2007-02-01 | — | — | WO | disclosed |
| EP-1351936-A1 | ARYL PIPERIDINE AND PIPERAZINE DERIVATIVES AS INDUCERS OF LDL-RECEPTOR EXPRESSION | GLAXO GROUP LIMITED (GB) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002055496-A1 | ARYL PIPERIDINE AND PIPERAZINE DERIVATIVES AS INDUCERS OF LDL-RECEPTOR EXPRESSION | GLAXO GROUP LIMITED (GB) | 2002-07-18 | — | — | WO | disclosed |