Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRB | P28702 | 2/20 | 0.70 |
| ▸ | RXRA | P19793 | 1/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.56 |
| ▸ | SORT1 | Q99523 | 10/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | CFTR | P13569 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Sulfide SCHEMBL27780391 | 0.98 | RXRB (0.68) | RXRBRXRAKDM4EALDH1A1HPGD | |
| SCHEMBL14089899 | 0.88 | RXRB (0.79) | RXRBRXRAKDM4EALDH1A1HPGD | |
| SCHEMBL710431 | 0.86 | TAS2R14 (0.59) | RXRBRXRAKDM4EALDH1A1HPGD | |
| SCHEMBL28191970 | 0.86 | RXRB (0.58) | RXRBRXRAKDM4EALDH1A1HPGD | |
| SCHEMBL3138225 | 0.85 | RXRB (0.57) | RXRBRXRAKDM4EALDH1A1HPGD | |
| SCHEMBL3023134 | 0.84 | CES2 (0.53) | RXRBRXRAKDM4EALDH1A1HPGD | |
| SCHEMBL18291815 | 0.84 | ALDH1A1 (0.56) | RXRBRXRAKDM4EALDH1A1HPGD | |
| SCHEMBL15549051 | 0.84 | RXRB (0.56) | RXRBRXRAKDM4EALDH1A1HPGD | |
| SCHEMBL3376888 | 0.84 | RXRB (0.64) | RXRBRXRAKDM4EALDH1A1HPGD | |
| SCHEMBL15549328 | 0.84 | RXRA (0.56) | RXRBRXRAKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4397763-A | TITANIUM-BASED | PHILLIPS PETROLEUM COMPANY (US) | 1983-08-09 | — | — | US | claimed |
| US-4330648-A | MIXTURE OF TITANIUM HALIDE, MAGNESIUM OR MANGANOUS CHLORIDE DIHYDROCARBYLALUMINUM HALIDE OR HYDRIDE AND AN ETHER-ALCOHOL | PHILLIPS PETROLEUM COMPANY (US) | 1982-05-18 | — | — | US | claimed |
| US-4312784-A | TITANIUM HALIDE, LEWIS BASE, MAGNESIUM OR MANGANOUS CHLORIDE, UNSATURATED HYDROCARBON AND TRIHYDROCARBYLALUMNIUM | PHILLIPS PETROLEUM CO. (US) | 1982-01-26 | — | — | US | claimed |
| US-4242480-A | TWO OR THREE COMPONENT SYSTEM COMPRISING A TITANIUM HALIDE, LEWIS BASE, MAGNESIUM OR MANGANESE CHLORIDE, UNSATURATED HYDROCARBON, ORGANOALUMINUM COMPOUND | PHILLIPS PETROLEUM COMPANY (US) | 1980-12-30 | — | — | US | claimed |
| EP-0002522-A1 | Process for polymerizing butene-1 | PHILLIPS PETROLEUM COMPANY (US) | 1979-06-27 | — | — | EP | claimed |
| EP-0002521-A1 | Titanium-magnesium/manganese-aluminum catalyst and process for olefin polymerization | PHILLIPS PETROLEUM COMPANY (US) | 1979-06-27 | — | — | EP | claimed |
| US-12435078-B2 | Pyridazinones and methods of use thereof | GFB (ABC), LLC (US) | 2025-10-07 | — | — | US | disclosed |
| WO-2025137158-A1 | DERIVATIVES OF ([1,2,4]TRIAZOLO[5,1-A]ISOQUINOLINE-5-CARBONYL)GLYCINATE AS PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | AKEBIA THERAPEUTICS, INC. (US) | 2025-06-26 | — | — | WO | disclosed |
| US-20250171420-A1 | MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME | MONTE ROSA THERAPEUTICS AG (CH) | 2025-05-29 | — | — | US | disclosed |
| EP-4540240-A1 | MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME | Monte Rosa Therapeutics AG (CH) | 2025-04-23 | — | — | EP | disclosed |
| CN-116003309-B | Hydrazide compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2025-03-04 | — | — | CN | disclosed |
| US-20240409573-A1 | CALICHEAMICIN DERIVATIVES AND ANTIBODY DRUG CONJUGATES THEREOF | PFIZER INC. (US) | 2024-12-12 | — | — | US | disclosed |
| US-11993625-B2 | Calicheamicin derivatives and antibody drug conjugates thereof | PFIZER, INC. (US) | 2024-05-28 | — | — | US | disclosed |
| WO-2001070671-A2 | INSECTICIDAL ANTHRANILAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2001-09-27 | — | — | WO | disclosed |
| CN-1310714-A | Substituted Benzoylcyclohexanediones | BAYER AG (DE) | 2001-08-29 | — | — | CN | disclosed |
| EP-1100789-A1 | SUBSTITUTED BENZOYLCYCLOHEXANDIONES | BAYER AG (DE) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000068227-A1 | SUBSTITUTED BENZOYLISOXAZOLES AND THE USE THEREOF AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-11-16 | — | — | WO | disclosed |
| WO-2000058306-A1 | SUBSTITUTED BENZOYLPYRAZOLES AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-10-05 | — | — | WO | disclosed |
| WO-2000005221-A1 | SUBSTITUTED BENZOYLCYCLOHEXANDIONES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-02-03 | — | — | WO | disclosed |
| WO-1997027187-A1 | ISOXAZOLE AND 2-CYANO-1,3-DIONES DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240409573-A1 | CALICHEAMICIN DERIVATIVES AND ANTIBODY DRUG CONJUGATES THEREOF | STT3A, CLSPN, STT3B | RXRB 4606/4885RXRA 4391/4885KDM4E 2561/4885 |
| US-11993625-B2 | Calicheamicin derivatives and antibody drug conjugates thereof | STT3A, CLSPN, STT3B | RXRB 4606/4885RXRA 4391/4885KDM4E 2561/4885 |
| US-12435078-B2 | Pyridazinones and methods of use thereof | PDXK, ATP6V1B1, REN | RXRB 961/4885RXRA 893/4885KDM4E 3899/4885 |
| US-20250171420-A1 | MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME | PSMA1, CSNK1G1, CSNK1A1 | RXRB 3013/4885RXRA 2845/4885KDM4E 394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.