Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16268838 | 0.85 | GAA (0.33) | GAA | |
| SCHEMBL20228829 | 0.81 | CYP11B1 (0.36) | GAAKDM4EL3MBTL1 | |
| SCHEMBL19946508 | 0.76 | — | — | |
| SCHEMBL1401020 | 0.76 | — | — | |
| SCHEMBL4925004 | 0.74 | POLB (0.47) | GAACTSK | |
| SCHEMBL1802879 | 0.73 | GAA (0.33) | GAAKDM4EL3MBTL1 | |
| SCHEMBL13282119 | 0.72 | NEK2 (0.46) | CTSK | |
| SCHEMBL2746220 | 0.70 | CTSK (0.39) | KDM4ECTSK | |
| SCHEMBL18630670 | 0.68 | — | — | |
| SCHEMBL15721209 | 0.67 | NEK2 (0.52) | KDM4EL3MBTL1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013010453-A1 | CHEMOKING RECEPTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 2013-01-24 | — | — | WO | disclosed |
| WO-2012000608-A2 | NOVEL BETA-AMINOALDEHYDE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR CHEMICAL USE AS REACTIVE INTERMEDIATES | GLUESENKAMP KARL-HEINZ (DE) | 2012-01-05 | — | — | WO | disclosed |