Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31267818 | 0.82 | — | — | |
| SCHEMBL1803215 | 0.76 | GAA (0.35) | GAAL3MBTL1 | |
| SCHEMBL13414719 | 0.75 | MEN1 (0.33) | — | |
| SCHEMBL1803997 | 0.75 | ALDH1A1 (0.37) | — | |
| SCHEMBL16268838 | 0.74 | GAA (0.33) | GAA | |
| SCHEMBL3376973 | 0.73 | GAA (0.39) | GAAKDM4EL3MBTL1 | |
| SCHEMBL2558905 | 0.72 | ESR2 (0.35) | GAAKDM4EL3MBTL1 | |
| SCHEMBL13414708 | 0.71 | CYP1A2 (0.31) | — | |
| SCHEMBL31267848 | 0.67 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL16161501 | 0.65 | KDM4E (0.34) | KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2984084-B1 | HIGHLY EFFICIENT POLARIZING AGENTS FOR DYNAMIC NUCLEAR POLARIZATION | BRUKER FRANCE S A S (FR) | 2022-05-04 | — | — | EP | disclosed |
| EP-2984084-B1 | HIGHLY EFFICIENT POLARIZING AGENTS FOR DYNAMIC NUCLEAR POLARIZATION | BRUKER FRANCE S A S (FR) | 2022-05-04 | — | — | EP | disclosed |
| US-9738657-B2 | Highly efficient polarizing agents for dynamic nuclear polarization | Bruker BioSpin S.A.S. (FR) | 2017-08-22 | — | — | US | disclosed |
| US-9738657-B2 | Highly efficient polarizing agents for dynamic nuclear polarization | Bruker BioSpin S.A.S. (FR) | 2017-08-22 | — | — | US | disclosed |
| US-9738657-B2 | Highly efficient polarizing agents for dynamic nuclear polarization | Bruker BioSpin S.A.S. (FR) | 2017-08-22 | — | — | US | disclosed |
| US-20160046643-A1 | HIGHLY EFFICIENT POLARIZING AGENTS FOR DYNAMIC NUCLEAR POLARIZATION | Bruker BioSpin S.A.S. (FR) | 2016-02-18 | — | — | US | disclosed |
| US-20160046643-A1 | HIGHLY EFFICIENT POLARIZING AGENTS FOR DYNAMIC NUCLEAR POLARIZATION | Bruker BioSpin S.A.S. (FR) | 2016-02-18 | — | — | US | disclosed |
| US-20160046643-A1 | HIGHLY EFFICIENT POLARIZING AGENTS FOR DYNAMIC NUCLEAR POLARIZATION | Bruker BioSpin S.A.S. (FR) | 2016-02-18 | — | — | US | disclosed |
| EP-2984084-A1 | HIGHLY EFFICIENT POLARIZING AGENTS FOR DYNAMIC NUCLEAR POLARIZATION | Bruker Biospin (SAS) (FR) | 2016-02-17 | — | — | EP | disclosed |
| WO-2014167121-A1 | HIGHLY EFFICIENT POLARIZING AGENTS FOR DYNAMIC NUCLEAR POLARIZATION | Bruker BioSpin S.A.S. (FR) | 2014-10-16 | — | — | WO | disclosed |
| WO-2014167121-A1 | HIGHLY EFFICIENT POLARIZING AGENTS FOR DYNAMIC NUCLEAR POLARIZATION | Bruker BioSpin S.A.S. (FR) | 2014-10-16 | — | — | WO | disclosed |
| EP-2789609-A1 | Highly efficient polarizing agents for dynamic nuclear polarization | Bruker Biospin (SAS) (FR) | 2014-10-15 | — | — | EP | disclosed |
| EP-2789609-A1 | Highly efficient polarizing agents for dynamic nuclear polarization | Bruker Biospin (SAS) (FR) | 2014-10-15 | — | — | EP | disclosed |
| US-8513417-B2 | Method for synthesis of nitroxyl radical | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2013-08-20 | — | — | US | disclosed |
| US-8513417-B2 | Method for synthesis of nitroxyl radical | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2013-08-20 | — | — | US | disclosed |
| WO-2011052759-A1 | NOVEL NITROXYL RADICAL COMPOUND AND PROCESS FOR PRODUCTION THEREOF | 国立大学法人九州大学 (JP) | 2011-05-05 | — | — | WO | disclosed |
| US-20100076190-A1 | METHOD FOR SYNTHESIS OF NITROXYL RADICAL | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2010-03-25 | — | — | US | disclosed |
| US-20100076190-A1 | METHOD FOR SYNTHESIS OF NITROXYL RADICAL | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2010-03-25 | — | — | US | disclosed |
| EP-2128135-A1 | METHOD FOR SYNTHESIS OF NITROXYL RADICAL | Kyushu University, National University Corporation (JP) | 2009-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076190-A1 | METHOD FOR SYNTHESIS OF NITROXYL RADICAL | NOX4, TXN2, TXNRD2 | GAA 3773/4885KDM4E 984/4885L3MBTL1 2372/4885 |
| US-20160046643-A1 | HIGHLY EFFICIENT POLARIZING AGENTS FOR DYNAMIC NUCLEAR POLARIZATION | NR2E3, NR2E1, NR4A2 | GAA 4704/4885KDM4E 3144/4885L3MBTL1 4459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.