Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.35 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.34 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.34 |
| ▸ | PPIA | P62937 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 2/20 | 0.30 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15295683 | 0.85 | CTSK (0.39) | CTSKPPIAMEN1KMT2ACTSL | |
| SCHEMBL3398195 | 0.85 | HPGD (0.39) | PPIAMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL3377077 | 0.83 | P2RX7 (0.40) | CTSKPPIAMEN1KMT2ACTSL | |
| SCHEMBL3375323 | 0.83 | P2RX7 (0.38) | CTSKPPIAMEN1KMT2ACTSL | |
| SCHEMBL3374268 | 0.81 | P2RX7 (0.42) | CTSKPPIAMEN1KMT2ACTSL | |
| SCHEMBL3377080 | 0.81 | P2RX7 (0.42) | CTSKPPIAMEN1KMT2ACTSL | |
| SCHEMBL3373789 | 0.81 | P2RX7 (0.42) | CTSKPPIAMEN1KMT2ACTSL | |
| SCHEMBL3377787 | 0.81 | P2RX7 (0.42) | CTSKPPIAMEN1KMT2ACTSL | |
| SCHEMBL7832081 | 0.80 | P2RX7 (0.41) | CTSKPPIAMEN1KMT2ACTSL | |
| SCHEMBL27648998 | 0.80 | JAK2 (0.37) | CTSKCTSLCTSDCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012000608-A2 | NOVEL BETA-AMINOALDEHYDE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR CHEMICAL USE AS REACTIVE INTERMEDIATES | GLUESENKAMP KARL-HEINZ (DE) | 2012-01-05 | — | — | WO | disclosed |