Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.72 |
| ▸ | FAAH | O00519 | 6/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3375838 | 0.88 | FAAH (0.56) | CNR2FAAHKMT2AMEN1ATM | |
| SCHEMBL2638506 | 0.88 | FAAH (0.75) | CNR2FAAHKMT2AMEN1ATM | |
| SCHEMBL3378038 | 0.86 | FAAH (0.54) | CNR2FAAHKMT2AMEN1ATM | |
| SCHEMBL1881827 | 0.81 | GRM5 (0.53) | CNR2FAAHKMT2AMEN1ATM | |
| SCHEMBL14503290 | 0.80 | FAAH (0.82) | CNR2FAAHKMT2AMEN1ATM | |
| SCHEMBL2638957 | 0.80 | KMT2A (1.00) | CNR2FAAHKMT2AMEN1ATM | |
| SCHEMBL19354776 | 0.77 | FAAH (0.72) | CNR2FAAHKMT2AMEN1ATM | |
| SCHEMBL1578586 | 0.77 | CNR2 (0.85) | CNR2FAAHKMT2AMEN1ATM | |
| SCHEMBL3375702 | 0.77 | FAAH (0.58) | CNR2FAAHKMT2AMEN1ATM | |
| SCHEMBL13333538 | 0.76 | ALDH1A1 (0.53) | CNR2FAAHKMT2AMEN1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011570-A1 | ADAMANTYL DIAMIDE DERIVATIVES AND USES OF SAME | H. LUNDBECK A/S (DK) | 2010-01-28 | — | — | WO | disclosed |