SCHEMBL337778

SCHEMBL337778

O=C(O)c1c(O)ccc2[nH]nnc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA7 P43166 2/20 0.41
CA9 Q16790 2/20 0.41
CA14 Q9ULX7 2/20 0.41
KDM4E B2RXH2 3/20 0.33
L3MBTL1 Q9Y468 3/20 0.33
KDM4A O75164 2/20 0.33
EGLN1 Q9GZT9 2/20 0.33
DPP4 P27487 1/20 0.33
KDM6B O15054 1/20 0.33
KDM6A O15550 1/20 0.33
TET3 O43151 1/20 0.33
KDM4B O94953 1/20 0.33
KDM5C P41229 1/20 0.33
KDM4D Q6B0I6 1/20 0.33
TET2 Q6N021 1/20 0.33
ALKBH5 Q6P6C2 1/20 0.33
TET1 Q8NFU7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8908207 0.87 ALDH1A1 (0.30)
SCHEMBL8953072 0.82 CYP1A2 (0.35) KDM4EL3MBTL1KDM4AEGLN1KDM6B
SCHEMBL6052154 0.81 DPP4 (0.48) CA12KDM4EDPP4KDM4CHCAR2
SCHEMBL6052065 0.81 ALPL (0.36) CA1CA2CA9L3MBTL1EGLN1
SCHEMBL6052047 0.81 HCAR2 (0.32) KDM4EL3MBTL1KDM4AKDM6BKDM4D
SCHEMBL11055544 0.81 HCAR2 (0.32) KDM4EL3MBTL1KDM4AKDM6BKDM4D
SCHEMBL9165897 0.79 DPP4 (0.47) CA12KDM4EDPP4KDM4CHCAR2
SCHEMBL9172736 0.79 ALPL (0.36) CA1CA2CA9L3MBTL1EGLN1
SCHEMBL9171604 0.79 HCAR2 (0.32) KDM4EHCAR2POLBMAPTALPL
SCHEMBL2529111 0.79 ALPL (0.39) CA9KDM4EPOLBGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8097164-B2 Process for preparing magnetic particles for selectively removing contaminants from solution ELECTRIC POWER RESEARCH INSTITUTE, INC. (US) 2012-01-17 US disclosed
EP-2063433-B1 Process for preparing magnetic particles for selectively removing contaminants from solution ELECTRIC POWER RES INST (US) 2010-06-09 EP disclosed
EP-2063433-A1 Process for preparing magnetic particles for selectively removing contaminants from solution Electric Power Research Institute, Inc. (US) 2009-05-27 EP disclosed
US-20090120880-A1 Process for Preparing Magnetic Particles for Selectively Removing Contaminants from Solution ELECTRIC POWER RESEARCH INSTITUTE, INC. 2009-05-14 US disclosed