Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 1/20 | 0.53 |
| ▸ | PRKDC | P78527 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | ATR | Q13535 | 1/20 | 0.53 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.41 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3412945 | 0.89 | SCN5A (0.46) | PIK3CBPRKDCATMATRATRIP | |
| SCHEMBL3474781 | 0.80 | PDE10A (0.44) | PIK3CBPRKDCATMATRATRIP | |
| SCHEMBL3433560 | 0.79 | MAPK14 (0.46) | PIK3CBPRKDCATMATRATRIP | |
| SCHEMBL3377951 | 0.78 | MAPK14 (0.45) | PIK3CBPRKDCATMATRATRIP | |
| SCHEMBL3434956 | 0.78 | ALDH1A1 (0.54) | PIK3CBPRKDCATMATRATRIP | |
| SCHEMBL3346267 | 0.77 | PPARG (0.49) | GRIN1GRIN2BPDE10AMAPK14DHODH | |
| SCHEMBL3379857 | 0.77 | KDM5A (0.43) | PIK3CBPRKDCATMATRATRIP | |
| SCHEMBL3347817 | 0.74 | ELANE (0.45) | GRIN1GRIN2BPDE10AMAPK14DHODH | |
| SCHEMBL3435814 | 0.74 | TRPC5 (0.47) | GRIN1GRIN2BPDE10AMETMAPK14 | |
| SCHEMBL3434425 | 0.74 | GRIN2B (0.50) | GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053757-A1 | 2 -OXOQUINOXALIN BLOCKERS OF THE LATE SODIUM CHANNEL | GILEAD PALO ALTO, INC. (US) | 2010-05-14 | — | — | WO | disclosed |