Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL28080804 | 0.96 | CHRM1 (0.38) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Ether SCHEMBL107913 | 0.88 | ALDH1A1 (0.35) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Acetic Acid SCHEMBL11353114 | 0.88 | CHRM1 (0.50) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Acetic Acid SCHEMBL11353075 | 0.88 | CHRM1 (0.50) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Ether SCHEMBL23130890 | 0.87 | ALDH1A1 (0.42) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Acetic Acid SCHEMBL3382899 | 0.86 | CHRM1 (0.44) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Acetic Acid SCHEMBL28196090 | 0.85 | CHRM1 (0.48) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Acetic Acid SCHEMBL29215809 | 0.85 | CHRM1 (0.48) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Ether SCHEMBL1786734 | 0.85 | HSD17B10 (0.33) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Ethyl Acetate SCHEMBL143987 | 0.85 | ALDH1A1 (0.56) | CHRM1AKR1A1CHRM3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641430-B | Photocatalyst laminate | 信越化学工业株式会社 | 2022-03-11 | — | — | CN | disclosed |
| CN-109803826-B | Laminate and method for producing same | 信越化学工业株式会社 | 2021-05-11 | — | — | CN | disclosed |
| CN-110248750-A | The manufacturing method of copper powder, resin combination, the method and solidfied material for forming solidfied material | 株式会社ADEKA | 2019-09-17 | — | — | CN | disclosed |
| CN-107075681-B | Copper film forms the manufacturing method of the copper film with composition and using it | 株式会社ADEKA | 2019-04-23 | — | — | CN | disclosed |
| CN-106795630-B | Copper film forms the manufacturing method of the copper film with composition and using it | 株式会社ADEKA | 2019-04-02 | — | — | CN | disclosed |
| CN-108250208-A | Dibenzo [b] furan compound, photoelectric conversion material and photo-electric conversion element | 株式会社艾迪科 | 2018-07-06 | — | — | CN | disclosed |
| CN-105980599-B | Composition for forming copper film and method for producing copper film using same | 株式会社ADEKA | 2018-05-15 | — | — | CN | disclosed |
| CN-107922589-A | Resin composition and cured product | 株式会社ADEKA | 2018-04-17 | — | — | CN | disclosed |
| CN-107614481-A | The preparation of high conductivity copper film | 加拿大国家研究委员会 | 2018-01-19 | — | — | CN | disclosed |
| CN-107075681-A | Copper film formation composition and the manufacture method using its copper film | 株式会社ADEKA | 2017-08-18 | — | — | CN | disclosed |
| CN-106795630-A | Copper film formation composition and the manufacture method using its copper film | 株式会社ADEKA | 2017-05-31 | — | — | CN | disclosed |
| CN-105980599-A | Composition for forming copper film and method for producing copper film using same | 株式会社ADEKA | 2016-09-28 | — | — | CN | disclosed |
| CN-104364290-B | Hardening resin composition, resin combination, resin sheet and these compositions and the solidfied material of resin sheet | ADEKA株式会社 | 2016-09-07 | — | — | CN | disclosed |
| CN-105802487-A | Actinic energy radiation-curable acrylic silicone resin composition and coated article | 信越化学工业株式会社 | 2016-07-27 | — | — | CN | disclosed |
| CN-105009227-A | OXIDE SUPERCONDUCTOR COMPOSITION, OXIDE SUPERCONDUCTOR WIRE, AND PRODUCTION METHOD FOR OXIDE SUPERCONDUCTOR WIRE | INT SUPERCONDUCTIVITY TECH | 2015-10-28 | — | — | CN | disclosed |
| EP-2009070-B1 | Ink-jet ink and method of producing the same, color filter and method of producing the same, display device, and method of forming functional film | FUJIFILM CORP (JP) | 2010-11-24 | — | — | EP | disclosed |
| US-20090035535-A1 | INK-JET INK AND METHOD OF PRODUCING THE SAME, COLOR FILTER AND METHOD OF PRODUCING THE SAME, DISPLAY DEVICE, AND METHOD OF FORMING FUNCTIONAL FILM | FUJIFILM CORPORATION (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-2009070-A1 | Ink-jet ink and method of producing the same, color filter and method of producing the same, display device, and method of forming functional film | FUJIFILM Corporation (JP) | 2008-12-31 | — | — | EP | disclosed |