Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.46 |
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3380426 | 0.88 | ALDH1A1 (0.47) | MAPK1ALDH1A1HPGDTP53TSHR | |
| SCHEMBL27898136 | 0.84 | MAPK1 (0.53) | MAPK1ALDH1A1HPGDTP53TSHR | |
| SCHEMBL1913458 | 0.83 | TSHR (0.51) | ALDH1A1HPGDTSHRSMN1; SMN2GPR35 | |
| SCHEMBL8616788 | 0.81 | ALDH1A1 (0.51) | ALDH1A1TSHRSMN1; SMN2MAPTLMNA | |
| SCHEMBL305116 | 0.80 | MAPT (0.61) | MAPK1ALDH1A1HPGDTP53TSHR | |
| SCHEMBL8372593 | 0.75 | ALDH1A1 (0.56) | MAPK1ALDH1A1HPGDTP53TSHR | |
| SCHEMBL27598146 | 0.75 | ALDH1A1 (0.51) | MAPK1ALDH1A1HPGDTP53TSHR | |
| SCHEMBL10750890 | 0.75 | ALDH1A1 (0.44) | MAPK1ALDH1A1HPGDTP53TSHR | |
| SCHEMBL11140206 | 0.74 | MAPK1 (0.50) | MAPK1ALDH1A1HPGDTP53TSHR | |
| SCHEMBL8318666 | 0.74 | ALDH1A1 (0.63) | MAPK1ALDH1A1HPGDTP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1429715-B1 | HAIR COLOURING COMPOSITIONS | BOOTS CO PLC (GB) | 2010-11-24 | — | — | EP | claimed |
| US-7172632-B2 | Hair coloring compositions | THE BOOTS COMPANY, PLC (GB) | 2007-02-06 | — | — | US | claimed |
| US-20050039269-A1 | Hair colouring compositions | BOOTS COMPANY PLC, THE (GB) | 2005-02-24 | — | — | US | claimed |
| EP-1429715-A2 | HAIR COLOURING COMPOSITIONS | The Boots Company PLC (GB) | 2004-06-23 | — | — | EP | claimed |
| WO-2003015734-A2 | HAIR COLOURING COMPOSITIONS | THE BOOTS COMPANY PLC (GB) | 2003-02-27 | — | — | WO | claimed |
| EP-1429715-B1 | HAIR COLOURING COMPOSITIONS | BOOTS CO PLC (GB) | 2010-11-24 | — | — | EP | disclosed |
| US-7172632-B2 | Hair coloring compositions | THE BOOTS COMPANY, PLC (GB) | 2007-02-06 | — | — | US | disclosed |
| US-20050039269-A1 | Hair colouring compositions | BOOTS COMPANY PLC, THE (GB) | 2005-02-24 | — | — | US | disclosed |
| EP-1429715-A2 | HAIR COLOURING COMPOSITIONS | The Boots Company PLC (GB) | 2004-06-23 | — | — | EP | disclosed |
| WO-2003015734-A2 | HAIR COLOURING COMPOSITIONS | THE BOOTS COMPANY PLC (GB) | 2003-02-27 | — | — | WO | disclosed |