Sugi Predict

Sugi Predict / Compounds / SCHEMBL1913458

SCHEMBL1913458

SCHEMBL1913458

CCN(O)c1ccc(N)c([N+](=O)[O-])c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 1/20 0.51
▸ MAPT P10636 6/20 0.50
▸ ALDH1A1 P00352 5/20 0.50
▸ TDP1 Q9NUW8 3/20 0.50
▸ MEN1 O00255 3/20 0.50
▸ KMT2A Q03164 3/20 0.50
▸ POLB P06746 2/20 0.50
▸ CYP3A4 P08684 1/20 0.50
▸ ALOX15 P16050 1/20 0.50
▸ PKM P14618 1/20 0.48
▸ LMNA P02545 3/20 0.47
▸ ADRB2 P07550 1/20 0.45
▸ PGR P06401 1/20 0.40
▸ CYP1A2 P05177 1/20 0.40
▸ CYP2C9 P11712 1/20 0.40
▸ CYP2C19 P33261 1/20 0.40
▸ RECQL P46063 1/20 0.39
▸ GAA P10253 1/20 0.39
▸ HPGD P15428 1/20 0.39
▸ HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3378073 0.83 MAPK1 (0.50) TSHRMAPTALDH1A1MEN1KMT2A
SCHEMBL2169229 0.81 LMNA (0.51) TSHRMAPTALDH1A1TDP1MEN1
SCHEMBL8616788 0.80 ALDH1A1 (0.51) TSHRMAPTALDH1A1TDP1MEN1
SCHEMBL976044 0.78 MAPT (0.61) TSHRMAPTALDH1A1TDP1MEN1
SCHEMBL31327401 0.78 MAPT (0.61) TSHRMAPTALDH1A1TDP1MEN1
SCHEMBL22115093 0.78 TSHR (0.51) TSHRMAPTALDH1A1TDP1MEN1
SCHEMBL28956910 0.77 TSHR (0.50) TSHRMAPTALDH1A1TDP1MEN1
SCHEMBL77877 0.76 LMNA (0.43) TSHRMAPTALDH1A1TDP1MEN1
Hydrochloric Acid SCHEMBL27885809 0.76 TSHR (0.49) TSHRMAPTALDH1A1TDP1MEN1
SCHEMBL127252 0.75 TDP1 (0.62) TSHRMAPTALDH1A1TDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4362906-A1 COMPOSITION COMPRISING SHEA, AN ALKYL(POLY)GLYCOSIDE, A POLYSACCHARIDE AND A DYE L'OREAL (FR) 2024-05-08 — — EP disclosed
WO-2023275187-A1 COMPOSITION COMPRISING SHEA, AN ALKYL(POLY)GLYCOSIDE, A POLYSACCHARIDE AND A DYE L'OREAL (FR) 2023-01-05 — — WO disclosed
WO-2023275170-A1 COMPOSITION COMPRISING AT LEAST ONE ALKANOLAMINE, A (META)SILICATE, GLYCINE AND 1,3-PROPANEDIOL L'OREAL (FR) 2023-01-05 — — WO disclosed
US-9578944-B2 Compositions and methods for altering the appearance of hair L'OREAL (FR) 2017-02-28 — — US disclosed
US-9565915-B2 Compositions and methods for altering the appearance of hair L'OREAL (FR) 2017-02-14 — — US disclosed
US-9565916-B2 Compositions and methods for altering the appearance of hair L'OREAL (FR) 2017-02-14 — — US disclosed
US-9566221-B2 Methods for altering the color and appearance of hair L'OREAL (FR) 2017-02-14 — — US disclosed
US-20150265513-A1 METHODS FOR ALTERING THE COLOR AND APPEARANCE OF HAIR L'OREAL (FR) 2015-09-24 — — US disclosed
US-20140326270-A1 COMPOSITIONS AND METHODS FOR ALTERING THE APPEARANCE OF HAIR L'OREAL (FR) 2014-11-06 — — US disclosed
US-20140311517-A1 COMPOSITIONS AND METHODS FOR ALTERING THE APPEARANCE OF HAIR L'OREAL (FR) 2014-10-23 — — US disclosed
WO-2013071192-A1 COMPOSITIONS AND METHODS FOR ALTERING THE APPEARANCE OF HAIR L'OREAL (FR) 2013-05-16 — — WO disclosed
WO-2013071194-A1 COMPOSITIONS AND METHODS FOR ALTERING THE APPEARANCE OF HAIR L'OREAL (FR) 2013-05-16 — — WO disclosed
WO-2013071196-A1 COMPOSITIONS AND METHODS FOR ALTERING THE APPEARANCE OF HAIR L'OREAL (FR) 2013-05-16 — — WO disclosed
WO-2013071191-A1 COMPOSITIONS AND METHODS FOR ALTERING THE APPEARANCE OF HAIR L'OREAL (FR) 2013-05-16 — — WO disclosed
WO-2013071182-A1 COMPOSITIONS AND METHODS FOR ALTERING THE APPEARANCE OF HAIR L'OREAL (FR) 2013-05-16 — — WO disclosed
EP-2575754-A2 COSMETIC TREATMENT PROCESS USING A COATING BASED ON A COPOLYMER CONTAINING POLYAMIDE BLOCKS AND POLYETHER BLOCKS L'Oréal (FR) 2013-04-10 — — EP disclosed
EP-2516013-A1 AGENT IN TWO OR MORE PARTS, IN EMULSION FORM, FOR DYEING AND/OR BLEACHING KERATIN FIBRES L'Oréal (FR) 2012-10-31 — — EP disclosed
WO-2011076647-A2 INVERSE EMULSION FOR TREATING THE HAIR COMPRISING A PARTICULAR FATTY SUBSTANCE AND AN ALKALINE AGENT L'OREAL (FR) 2011-06-30 — — WO disclosed
WO-2011076646-A2 AGENT FOR DYEING AND/OR BLEACHING KERATIN FIBRES, COMPRISING AN INVERSE EMULSION COMPRISING AN OXIDIZING AGENT L'OREAL (FR) 2011-06-30 — — WO disclosed
WO-2011076665-A1 AGENT IN TWO OR MORE PARTS, IN EMULSION FORM, FOR DYEING AND/OR BLEACHING KERATIN FIBRES L'OREAL (FR) 2011-06-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150265513-A1 METHODS FOR ALTERING THE COLOR AND APPEARANCE OF HAIR COXFA4L2, TYR, COX5A TSHR 4564/4885MAPT 2207/4885ALDH1A1 115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.