Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1726565 | 0.89 | KMT2A (0.42) | LMNAKMT2AMEN1FNTAFNTB | |
| SCHEMBL303569 | 0.84 | LMNA (0.46) | LMNASMN1; SMN2HTTKMT2AHPGD | |
| SCHEMBL1722793 | 0.82 | LMNA (0.47) | LMNASMN1; SMN2HTTKMT2AHPGD | |
| SCHEMBL3378147 | 0.81 | KMT2A (0.43) | LMNAKMT2AHPGDMEN1ALDH1A1 | |
| SCHEMBL1711184 | 0.79 | KMT2A (0.53) | LMNASMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL1722406 | 0.77 | LMNA (0.58) | LMNASMN1; SMN2HTTKMT2AHPGD | |
| SCHEMBL20394957 | 0.75 | NAMPT (0.40) | LMNASMN1; SMN2HTTKMT2AHPGD | |
| SCHEMBL306227 | 0.75 | TSHR (0.49) | LMNASMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL1725046 | 0.74 | LMNA (0.54) | LMNASMN1; SMN2HTTKMT2AHPGD | |
| SCHEMBL1723243 | 0.74 | LMNA (0.54) | LMNASMN1; SMN2HTTKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2012500834-A | — | — | 2012-01-12 | — | — | JP | claimed |
| EP-2344456-A1 | NOVEL POTASSIUM CHANNEL BLOCKER | Xention Limited (GB) | 2011-07-20 | — | — | EP | claimed |
| WO-2010023445-A1 | NOVEL POTASSIUM CHANNEL BLOCKER | XENTION LIMITED (GB) | 2010-03-04 | — | — | WO | claimed |