SCHEMBL3378474

SCHEMBL3378474

C=CCOCCSC[Si](C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
POLB P06746 1/20 0.38
KMT2A Q03164 1/20 0.38
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3339466 0.81 MEN1 (0.36) MEN1POLBKMT2A
SCHEMBL14914664 0.77 MEN1 (0.36) MEN1POLBKMT2A
SCHEMBL10593171 0.72 MEN1 (0.45) MEN1POLBKMT2AALDH1A1
SCHEMBL28142563 0.71 TDP1 (0.43) MEN1POLBKMT2A
SCHEMBL153914 0.67 POLB (0.52) MEN1POLBKMT2AALDH1A1
SCHEMBL29141576 0.66
SCHEMBL8747227 0.66 MEN1 (0.43) MEN1POLBKMT2AALDH1A1
SCHEMBL925201 0.64
SCHEMBL177611 0.64 POLB (0.50) MEN1POLBKMT2AALDH1A1
SCHEMBL7521085 0.64 POLB (0.50) MEN1POLBKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1452549-B1 PROCESS FOR PRODUCING MODIFIED POLYMER, APPARATUS FOR PRODUCING MODIFIED POLYMER, AND MODIFIED POLYMER SEKISUI CHEMICAL CO LTD (JP) 2010-11-17 EP disclosed
US-7629419-B2 Process for producing modified polymer, apparatus for producing modified polymer, and modified polymer SEKISUI CHEMICAL CO., LTD. (JP) 2009-12-08 US disclosed
CN-1289538-C Method for producing modified polymer compound, apparatus for producing modified polymer compound, and modified polymer compound SEKISUI CHEMICAL CO LTD (JP) 2006-12-13 CN disclosed
US-20050053792-A1 High purity; using supercritical fluid; high temperature; high pressure; polyolefins; interface film for glass; ceramic binder SEKISUI CHEMICAL CO., LTD. (JP) 2005-03-10 US disclosed
CN-1571801-A Process for producing modified polymer, apparatus for producing modified polymer, and modified polymer SEKISUI CHEMICAL CO LTD (JP) 2005-01-26 CN disclosed
EP-1452549-A1 PROCESS FOR PRODUCING MODIFIED POLYMER, APPARATUS FOR PRODUCING MODIFIED POLYMER, AND MODIFIED POLYMER SEKISUI CHEMICAL CO., LTD. (JP) 2004-09-01 EP disclosed