Butadiene

Butadiene

SCHEMBL337854

C=C(CC=Cc1ccccc1)C(=O)OC.C=CC=C

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAM P19021 1/20 0.51
MAOB P27338 4/20 0.48
MAOA P21397 3/20 0.43
LMNA P02545 1/20 0.41
CYP4F2 P78329 2/20 0.40
CYP4A11 Q02928 2/20 0.40
ALDH1A1 P00352 3/20 0.40
MAPT P10636 3/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
KDM4E B2RXH2 2/20 0.39
RECQL P46063 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
ALOX15 P16050 1/20 0.39
HDAC1 Q13547 1/20 0.39
NPC1 O15118 1/20 0.38
GLA P06280 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
APP P05067 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL96726 0.95 PAM (0.56) PAMMAOBMAOALMNACYP4F2
Acrylonitrile SCHEMBL3797624 0.92 PAM (0.44) PAMMAOBMAOALMNACYP4F2
Methacrylic Acid SCHEMBL491632 0.90 PAM (0.50) PAMMAOBMAOALMNACYP4F2
SCHEMBL678463 0.90 PAM (0.50) PAMMAOBMAOALMNACYP4F2
Acrylonitrile SCHEMBL3628806 0.89 PAM (0.46) PAMMAOBMAOALMNACYP4F2
1,4-Butanediol SCHEMBL10595488 0.89 PAM (0.49) PAMMAOBMAOALMNACYP4F2
SCHEMBL5496306 0.88 PAM (0.45) PAMMAOBMAOALMNACYP4F2
SCHEMBL4932016 0.88 PAM (0.45) PAMMAOBMAOALMNACYP4F2
SCHEMBL9478021 0.87 PAM (0.47) PAMMAOBMAOALMNACYP4F2
SCHEMBL11244981 0.87 PAM (0.42) PAMMAOBMAOALMNACYP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2091731-B1 PREPREG LAMINATES Henkel IP & Holding GmbH (DE) 2016-11-30 EP claimed
EP-1954759-B1 CURABLE COMPOSITIONS HENKEL CORP (US) 2011-03-30 EP claimed
JP-2010513057-A 2010-04-30 JP claimed
US-7649060-B2 Curable compositions HENKEL CORPORATION (US) 2010-01-19 US claimed
EP-2091731-A1 PREPREG LAMINATES Henkel Corporation (US) 2009-08-26 EP claimed
US-7537827-B1 Prepreg laminates HENKEL CORPORATION (US) 2009-05-26 US claimed
WO-2008076244-A1 PREPREG LAMINATES HENKEL CORPORATION (US) 2008-06-26 WO claimed
US-7320649-B2 Golf balls incorporating rigid, rosin-modified polymers ACUSHNET COMPANY (US) 2008-01-22 US claimed
US-20070129509-A1 Curable compositions HENKEL CORPORATION 2007-06-07 US claimed
US-5278257-A A blend of olefin-diolefin copolymer CIBA-GEIGY CORPORATION (US) 1994-01-11 US claimed
EP-0308664-B1 MODIFIED EPOXY RESINS CIBA-GEIGY AG (CH) 1991-08-28 EP claimed
WO-2024010749-A1 MODIFIERS FOR POLYESTERS THAT IMPROVE VISCOSITY IN MELT KANEKA AMERICAS HOLDING, INC. (US) 2024-01-11 WO disclosed
EP-3325533-B1 CURABLE BENZOXAZINE COMPOSITIONS HUNTSMAN ADVANCED MAT AMERICAS LLC (US) 2023-09-13 EP disclosed
CN-112423954-B Extrusion method for producing thermoplastic moulding materials and device for carrying out said method 英力士苯领集团股份公司 2023-08-08 CN disclosed
US-20230062748-A1 MODIFIERS FOR POLYESTERS THAT IMPROVE VISCOSITY IN MELT KANEKA AMERICAS HOLDING, INC. (US) 2023-03-02 US disclosed
US-4481332-A CONTAINING NITROGEN-CONTAINING MONOMER UNITS KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1984-11-06 US disclosed
US-4228250-A Blends of hydrolyzed ethylene-vinyl acetate resins having increased impact strength NATIONAL DISTILLERS AND CHEMICAL CORPORATION (US) 1980-10-14 US disclosed
US-4190687-A WITH COPOLYMER OF ETHYLENEICALLY UNSATURATED ESTER AND ETHYLENICALLY UNSATURATED HYDROCARBON TO PREVENT COLOR BLEEDING SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1980-02-26 US disclosed
US-4132050-A SUBSTRATE OF POLYPROPYLENE AND ETHYLENE-PROPYLENE BLOCK COPOLYMER, COATING OF HEAT SEALABLE MATERIAL, PACKAGING METHOD IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-01-02 US disclosed
US-4032497-A METHOD AND APPARATUS FOR REMOVAL OF UNREACTED MONOMER FROM SYNTHESIZED HIGH POLYMER LATEX KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JA) 1977-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070129509-A1 Curable compositions CBX4, CBX7, KDM5C PAM 1589/4885MAOB 1484/4885MAOA 670/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.