Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.61 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.58 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.58 |
| ▸ | ITGAL | P20701 | 3/20 | 0.58 |
| ▸ | GGT1 | P19440 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.52 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.51 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.51 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.51 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL151336 | 0.85 | ITGB2 (0.60) | CYP3A4SLC7A5ITGB2ICAM1ITGAL | |
| SCHEMBL29938832 | 0.85 | ITGB2 (0.60) | CYP3A4SLC7A5ITGB2ICAM1ITGAL | |
| SCHEMBL27413426 | 0.85 | ITGB2 (0.67) | CYP3A4SLC7A5ITGB2ICAM1ITGAL | |
| SCHEMBL17846596 | 0.85 | CYP3A4 (0.64) | CYP3A4SLC7A5ITGB2ICAM1ITGAL | |
| SCHEMBL163397 | 0.85 | ITGB2 (0.60) | CYP3A4SLC7A5ITGB2ICAM1ITGAL | |
| SCHEMBL27043238 | 0.85 | ITGB2 (0.60) | CYP3A4SLC7A5ITGB2ICAM1ITGAL | |
| Hydrochloric Acid SCHEMBL11744091 | 0.84 | ITGB2 (0.59) | CYP3A4SLC7A5ITGB2ICAM1ITGAL | |
| SCHEMBL28171998 | 0.83 | ITGB2 (0.58) | CYP3A4SLC7A5ITGB2ICAM1ITGAL | |
| SCHEMBL468830 | 0.83 | ITGB2 (0.64) | CYP3A4SLC7A5ITGB2ICAM1ITGAL | |
| SCHEMBL6026427 | 0.83 | ITGB2 (0.64) | CYP3A4SLC7A5ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120555-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | Heller, Adam (US) | 2009-11-25 | — | — | EP | claimed |
| US-20080287866-A1 | Methods and compositions for the treatment of pain | HELLER ADAM | 2008-11-20 | — | — | US | claimed |
| WO-2008094664-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2008-08-07 | — | — | WO | claimed |
| US-3991107-A | Haloamine transfer | NATIONAL PATENT DEVELOPMENT CORPORATION (US) | 1976-11-09 | — | — | US | claimed |
| US-20240091121-A1 | PHOSPHONATES AND N-HALAMINES COMPOSITIONS FOR TARTAR REMOVAL | O.Y.M. INNOVATION LTD. (IL) | 2024-03-21 | — | — | US | disclosed |
| CN-116710046-A | Phosphonic acid and N-halamine compositions for tartar removal | O.Y.M.创新有限公司 | 2023-09-05 | — | — | CN | disclosed |
| WO-2010017405-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2010-02-11 | — | — | WO | disclosed |
| EP-2120555-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | Heller, Adam (US) | 2009-11-25 | — | — | EP | disclosed |
| US-20080287866-A1 | Methods and compositions for the treatment of pain | HELLER ADAM | 2008-11-20 | — | — | US | disclosed |
| WO-2008094664-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2008-08-07 | — | — | WO | disclosed |
| US-3991107-A | Haloamine transfer | NATIONAL PATENT DEVELOPMENT CORPORATION (US) | 1976-11-09 | — | — | US | disclosed |
| US-3943628-A | Spoon excavator for applying chemically acting tooth decay attacking fluid | KRONMAN JOSEPH H | 1976-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240091121-A1 | PHOSPHONATES AND N-HALAMINES COMPOSITIONS FOR TARTAR REMOVAL | PHOSPHO1, PHPT1, PTMS | CYP3A4 4755/4885SLC7A5 1879/4885ITGB2 763/4885 |
| US-20080287866-A1 | Methods and compositions for the treatment of pain | ACHE, S100P, P2RX3 | CYP3A4 2737/4885SLC7A5 4883/4885ITGB2 2764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.