Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.48 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12239181 | 0.77 | SMO (0.33) | — | |
| SCHEMBL4620125 | 0.76 | TSHR (0.63) | LMNACYP3A4GABRA1TSHRGABRG2 | |
| SCHEMBL5212 | 0.76 | — | — | |
| SCHEMBL3381477 | 0.75 | LMNA (0.40) | LMNACYP3A4GABRA1TSHRGABRG2 | |
| SCHEMBL3378526 | 0.74 | LMNA (0.48) | LMNACYP3A4GABRA1TSHRGABRG2 | |
| SCHEMBL4327940 | 0.74 | LMNA (0.48) | LMNACYP3A4GABRA1TSHRGABRG2 | |
| SCHEMBL17159759 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL443213 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL27668202 | 0.72 | LMNA (0.46) | LMNACYP3A4GABRA1TSHRGABRG2 | |
| SCHEMBL5424 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017405-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2010-02-11 | — | — | WO | claimed |
| WO-2010017405-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2010-02-11 | — | — | WO | disclosed |