Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5269729 | 0.81 | ACHE (0.32) | SMOLTA4HIDO1ACHE | |
| SCHEMBL357188 | 0.77 | NCF1 (0.37) | IDO1 | |
| SCHEMBL3379118 | 0.77 | LMNA (0.48) | — | |
| SCHEMBL12706336 | 0.76 | TP53 (0.33) | IDO1 | |
| SCHEMBL23155733 | 0.75 | IDO1 (0.31) | SMOLTA4HIDO1ACHE | |
| SCHEMBL28026825 | 0.75 | IDO1 (0.34) | SMOLTA4HIDO1ACHE | |
| SCHEMBL19195506 | 0.75 | IDO1 (0.31) | SMOLTA4HIDO1ACHE | |
| SCHEMBL357187 | 0.75 | IDO1 (0.31) | SMOLTA4HIDO1ACHE | |
| Hydrochloric Acid SCHEMBL1902055 | 0.75 | NCF1 (0.36) | IDO1 | |
| SCHEMBL7353865 | 0.75 | IDO1 (0.31) | SMOLTA4HIDO1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9249180-B2 | C-3 alkyl and alkenyl modified betulinic acid derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-02-02 | — | — | US | disclosed |
| US-20110263557-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-10-27 | — | — | US | disclosed |
| US-20110263557-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | IRM LLC (BM) | 2011-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263557-A1 | COMPOUNDS AND COMPOSITIONS AS MODULATORS OF GPR119 ACTIVITY | GPR119, GPR55, NR1H2 | SMO 533/4885LTA4H 1689/4885IDO1 3092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.