⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15967967 | 1.00 | TSHR (0.30) | — | |
| SCHEMBL21179486 | 1.00 | TSHR (0.30) | — | |
| SCHEMBL635877 | 1.00 | TSHR (0.30) | — | |
| SCHEMBL97177 | 0.93 | — | — | |
| SCHEMBL2141485 | 0.86 | TSHR (0.30) | — | |
| SCHEMBL10990883 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL4986121 | 0.86 | TSHR (0.30) | — | |
| Bromide SCHEMBL10984057 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL10842729 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL4986134 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118994167-A | Imidazo [1,5-a ] pyrazine antitumor compound and preparation method and application thereof | 南京健康产业研究院 | 2024-11-22 | — | — | CN | claimed |
| CN-116655619-A | 2H-indazole compound and preparation method and application thereof | 南京康立凯医药科技有限公司 | 2023-08-29 | — | — | CN | claimed |
| CN-108530436-B | Pyrazole compound and preparation method and application thereof | 黄传满 | 2020-12-29 | — | — | CN | claimed |
| CN-119409682-A | 1H-indazole compound and preparation method and application thereof | 南京健康产业研究院 | 2025-02-11 | — | — | CN | disclosed |
| CN-118994167-A | Imidazo [1,5-a ] pyrazine antitumor compound and preparation method and application thereof | 南京健康产业研究院 | 2024-11-22 | — | — | CN | disclosed |
| US-20240239778-A1 | GRISEOFULVIN COMPOUND AND PHARMACEUTICAL USE THEREOF | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2024-07-18 | — | — | US | disclosed |
| CN-118251397-A | LRRK2 inhibitors | H.隆德贝克有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-118125995-A | Synthesis method of 1- (2-methoxyphenyl) piperazine hydrochloride | 南昌大学抚州医学院 | 2024-06-04 | — | — | CN | disclosed |
| US-20240150309-A1 | GRISEOFULVIN COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2024-05-09 | — | — | US | disclosed |
| CN-114456161-B | Imidazole derivative and organic electroluminescent device thereof | 长春海谱润斯科技股份有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-116655619-A | 2H-indazole compound and preparation method and application thereof | 南京康立凯医药科技有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-107408637-A | Charge-transporting film for organic electroluminescent device forms composition, charge-transporting film and organic electroluminescent device for organic electroluminescent device | 日产化学工业株式会社 | 2017-11-28 | — | — | CN | disclosed |
| CN-102471345-A | Pyrrolopyrazine inhibitors of kinases | ABBOTT LAB | 2012-05-23 | — | — | CN | disclosed |
| US-8097618-B2 | Pyridine derivatives and their use in the treatment of psychotic disorders | GLAXOSMITHKLINE LLC (US) | 2012-01-17 | — | — | US | disclosed |
| US-20110190276-A1 | Pyridine Derivatives And Their Use In The Treatment Of Psychotic Disorders | KaNDy Therapeutics Limited (GB) | 2011-08-04 | — | — | US | disclosed |
| US-7919491-B2 | Pyridine derivatives and their use in the treatment of psychotic disorders | GLAXOSMITHKLINE LLC (US) | 2011-04-05 | — | — | US | disclosed |
| US-20100152175-A1 | Pyridine Derivatives and Their Use in The Treatment of Psychotic Disorders | GLAXOSMITHKLINE LLC (US) | 2010-06-17 | — | — | US | disclosed |
| US-7683056-B2 | Pyridine derivatives and their use in the treatment of psychotic disorders | GLAXOSMITHKLINE LLC (US) | 2010-03-23 | — | — | US | disclosed |
| EP-1979311-A2 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | TRANSTECH PHARMA (US) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007071766-A2 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | TRANSTECH PHARMA (US) | 2007-06-28 | — | — | WO | disclosed |